Entity Details

Primary name NGEF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N5V2
EntryNameNGEF_HUMAN
FullNameEphexin-1
TaxID9606
Evidenceevidence at protein level
Length710
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesNGEF

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007399 nervous system development
GO:0016020 membrane
GO:0030154 cell differentiation
GO:0030426 growth cone
GO:0043065 positive regulation of apoptotic process
GO:0043087 regulation of GTPase activity
GO:0048013 ephrin receptor signaling pathway
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0061002 negative regulation of dendritic spine morphogenesis
GO:0090630 activation of GTPase activity

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035635 Ephexin-1, SH3 domainDomainDomain
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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