Entity Details

Primary name BMAL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00327
EntryNameBMAL1_HUMAN
FullNameAryl hydrocarbon receptor nuclear translocator-like protein 1
TaxID9606
Evidenceevidence at protein level
Length626
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesARNTL

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007283 spermatogenesis
GO:0007623 circadian rhythm
GO:0016605 PML body
GO:0017162 aryl hydrocarbon receptor binding
GO:0032007 negative regulation of TOR signaling
GO:0032922 circadian regulation of gene expression
GO:0033391 chromatoid body
GO:0034751 aryl hydrocarbon receptor complex
GO:0042634 regulation of hair cycle
GO:0042753 positive regulation of circadian rhythm
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0045599 negative regulation of fat cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0050767 regulation of neurogenesis
GO:0050796 regulation of insulin secretion
GO:0051726 regulation of cell cycle
GO:0051775 response to redox state
GO:0051879 Hsp90 protein binding
GO:0070888 E-box binding
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0090403 oxidative stress-induced premature senescence
GO:0120163 negative regulation of cold-induced thermogenesis
GO:0140297 DNA-binding transcription factor binding
GO:1901985 positive regulation of protein acetylation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000074 regulation of type B pancreatic cell development
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway
GO:2000772 regulation of cellular senescence
GO:2001016 positive regulation of skeletal muscle cell differentiation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR001067 Nuclear translocatorFamilyFamily
IPR001610 PAC motifRepeatRepeat
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR013767 PAS foldDomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

67 interactions

InteractorPartnerSourcesPublicationsLink
BMAL1_HUMANEPAS1_HUMANBioGRID, HPRD, IntAct11018023 32296183 9576906 details
BMAL1_HUMANCLOCK_HUMANBioGRID, HPRD, IntAct11018023 11439184 14701734 19922678 20551151 23555304 26164627 27173435 28388406 28514442 30287810 31515488 32296183 9576906 9989497 unassigned1312 details
BMAL1_HUMANNPAS2_HUMANBioGRID, HPRD, IntAct11439184 20211142 23555304 24722188 28514442 32296183 9576906 details
BMAL1_HUMANAZIN1_HUMANBioGRID, IntAct32296183 details
BMAL1_HUMANZMY12_HUMANBioGRID, IntAct32296183 details
BMAL1_HUMANTPC12_HUMANBioGRID, IntAct32296183 details
BMAL1_HUMANDHTK1_HUMANBioGRID, IntAct32296183 details
BMAL1_HUMANCRY1_HUMANBioGRID, HPRD, IntAct10531061 23555304 25756610 28388406 details
BMAL1_HUMANHIF1A_HUMANBioGRID, HPRD, IntAct25416956 31515488 9576906 details
BMAL1_HUMANNPAS4_HUMANBioGRID, HPRD14701734 details
BMAL1_HUMANEP300_HUMANBioGRID14645221 details
BMAL1_HUMANKAT2B_HUMANBioGRID14645221 details
BMAL1_HUMANKC1E_HUMANBioGRID, HPRD11875063 23555304 details
BMAL1_HUMANRXRA_HUMANBioGRID11439184 details
BMAL1_HUMANRARA_HUMANBioGRID11439184 details
BMAL1_HUMANAHR_HUMANBioGRID, HPRD9079689 details
BMAL1_HUMANHS90A_HUMANBioGRID, HPRD9079689 details
BMAL1_HUMANSIR1_HUMANBioGRID18662547 details
BMAL1_HUMANCRY2_HUMANBioGRID23555304 31155351 details
BMAL1_HUMANCSK2B_HUMANBioGRID23555304 26562092 details
BMAL1_HUMANWDR5_HUMANBioGRID23555304 details
BMAL1_HUMANRORG_HUMANBioGRID23555304 details
BMAL1_HUMANRHOU_HUMANBioGRID26598620 details
BMAL1_HUMANRHOA_HUMANBioGRID30287810 details
BMAL1_HUMANCSK21_HUMANBioGRID26562092 details
BMAL1_HUMANCHIP_HUMANBioGRID32041778 details
BMAL1_HUMANBHE40_HUMANHPRD12397359 15193144 details
BMAL1_HUMANHLF_HUMANHPRD9704006 details
BMAL1_HUMANPSMD9_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANGOGA5_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANDZIP3_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANHAUS6_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANPHLB3_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANVPS53_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANCCD93_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANGRAP1_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANGIT2_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANMAX_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANJUN_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANKDM1A_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANMS18B_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANRBG1L_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANCCHCR_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANPF21A_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANTHA11_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANNUF2_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANNCK5L_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANHM20A_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANTUFT1_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANVPS51_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANRCOR1_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANYETS4_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANTFPT_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANCAVN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANPKN3_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANVPS50_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANRPR1A_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANRABX5_HUMANBioGRID, IntAct27173435 unassigned1312 details
BMAL1_HUMANCBP_HUMANBioGRID, DIP24737000 26164627 details
BMAL1_HUMANHNF4A_HUMANIntAct30530698 details
BMAL1_HUMANUBE3A_HUMANBioGRID24728990 25660546 details
BMAL1_HUMANPP1A_HUMANBioGRID23555304 details
BMAL1_HUMANTRAF2_HUMANBioGRID29935055 details
BMAL1_HUMANUBE2O_HUMANBioGRID29871923 details
BMAL1_HUMANSYVN1_HUMANBioGRID32765757 details
BMAL1_HUMANPER3_HUMANHPRD14701732 details
BMAL1_HUMANUBC9_HUMANHPRD18644859 details