Entity Details

Primary name TRI38_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00635
EntryNameTRI38_HUMAN
FullNameE3 ubiquitin-protein ligase TRIM38
TaxID9606
Evidenceevidence at protein level
Length465
SequenceStatuscomplete
DateCreated2002-06-06
DateModified2021-06-02

Ontological Relatives

GenesTRIM38

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0003713 transcription coactivator activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008270 zinc ion binding
GO:0010468 regulation of gene expression
GO:0010508 positive regulation of autophagy
GO:0016567 protein ubiquitination
GO:0019901 protein kinase binding
GO:0032880 regulation of protein localization
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0046596 regulation of viral entry into host cell
GO:0046598 positive regulation of viral entry into host cell
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000315 B-box-type zinc fingerDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001870 B30.2/SPRY domainDomainDomain
IPR003877 SPRY domainDomainDomain
IPR003879 Butyrophylin-like, SPRY domainDomainDomain
IPR006574 SPRY-associatedDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR035790 E3 ubiquitin-protein ligase TRIM38, PRY/SPRY domainDomainDomain
IPR043136 B30.2/SPRY domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

38 interactions

InteractorPartnerSourcesPublicationsLink
TRI38_HUMANRIPK1_HUMANHPRD, MINT11854271 details
TRI38_HUMANUBE2U_HUMANBioGRID, IntAct19690564 details
TRI38_HUMANHS71A_HUMANBioGRID, IntAct21988832 23414517 details
TRI38_HUMANHS71B_HUMANBioGRID, IntAct21988832 23414517 details
TRI38_HUMANATX1_HUMANBioGRID, IntAct23275563 32814053 details
TRI38_HUMANSDCB1_HUMANBioGRID, IntAct25416956 details
TRI38_HUMANHSP7C_HUMANBioGRID, IntAct25416956 32296183 details
TRI38_HUMANRFC5_HUMANBioGRID, IntAct25416956 29892012 31515488 32296183 details
TRI38_HUMANHSP72_HUMANBioGRID, IntAct25416956 31515488 details
TRI38_HUMANSTXB1_HUMANBioGRID, IntAct25416956 25910212 32296183 details
TRI38_HUMANGORS2_HUMANBioGRID, IntAct25416956 32296183 details
TRI38_HUMANTSYL4_HUMANBioGRID, IntAct25416956 32296183 details
TRI38_HUMANTRI38_HUMANBioGRID, IntAct25416956 details
TRI38_HUMANHS71L_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANBYST_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANZN764_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANPSA4_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANTCEA2_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANMTURN_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANRNF4_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANPIAS4_HUMANBioGRID, IntAct32296183 details
TRI38_HUMANUB2D1_HUMANBioGRID21143188 details
TRI38_HUMANUB2D2_HUMANBioGRID21143188 details
TRI38_HUMANUB2D3_HUMANBioGRID21143188 details
TRI38_HUMANUB2D4_HUMANBioGRID21143188 details
TRI38_HUMANUB2E1_HUMANBioGRID21143188 details
TRI38_HUMANUB2E2_HUMANBioGRID21143188 details
TRI38_HUMANUB2E3_HUMANBioGRID21143188 details
TRI38_HUMANUBC9_HUMANBioGRID25416956 32296183 details
TRI38_HUMANEIF1B_HUMANBioGRID25416956 details
TRI38_HUMANGMCL1_HUMANBioGRID25416956 details
TRI38_HUMANTRAF6_HUMANBioGRID22323536 details
TRI38_HUMANTCAM1_HUMANBioGRID23056470 details
TRI38_HUMANTAB2_HUMANBioGRID24434549 details
TRI38_HUMANTAB3_HUMANBioGRID24434549 details
TRI38_HUMANAZI2_HUMANBioGRID22539786 details
TRI38_HUMANNLRP6_HUMANBioGRID28295271 details
TRI38_HUMANENTR1_HUMANBioGRID29395067 details