Entity Details

Primary name ALKB8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96BT7
EntryNameALKB8_HUMAN
FullNameAlkylated DNA repair protein alkB homolog 8
TaxID9606
Evidenceevidence at protein level
Length664
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesALKBH8

GO terms

Show/Hide Table
GOName
GO:0000049 tRNA binding
GO:0002098 tRNA wobble uridine modification
GO:0005506 iron ion binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006974 cellular response to DNA damage stimulus
GO:0008270 zinc ion binding
GO:0016300 tRNA (uracil) methyltransferase activity
GO:0016604 nuclear body
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0030488 tRNA methylation
GO:0106335 tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR005123 Oxoglutarate/iron-dependent dioxygenaseDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR013216 Methyltransferase type 11DomainDomain
IPR015095 Alkylated DNA repair protein AlkB, homologue 8, N-terminalDomainDomain
IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-likeDomainDomain
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily
IPR034256 ALKBH8, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

5 interactions