Entity Details

Primary name ARAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96P48
EntryNameARAP1_HUMAN
FullNameArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length1450
SequenceStatuscomplete
DateCreated2003-01-27
DateModified2021-06-02

Ontological Relatives

GenesARAP1

GO terms

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GOName
GO:0001921 positive regulation of receptor recycling
GO:0005096 GTPase activator activity
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005654 nucleoplasm
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0008360 regulation of cell shape
GO:0030037 actin filament reorganization involved in cell cycle
GO:0031410 cytoplasmic vesicle
GO:0031702 type 1 angiotensin receptor binding
GO:0032580 Golgi cisterna membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0043547 positive regulation of GTPase activity
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0046872 metal ion binding
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051270 regulation of cellular component movement
GO:0051491 positive regulation of filopodium assembly
GO:0051497 negative regulation of stress fiber assembly

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001164 Arf GTPase activating proteinDomainDomain
IPR001660 Sterile alpha motif domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR037858 ARAP, RhoGAP domainDomainDomain
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily

Diseases

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