Entity Details

Primary name AGAP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99490
EntryNameAGAP2_HUMAN
FullNameArf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
TaxID9606
Evidenceevidence at protein level
Length1192
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesAGAP2

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005096 GTPase activator activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0015031 protein transport
GO:0016020 membrane
GO:0016197 endosomal transport
GO:0019901 protein kinase binding
GO:0030036 actin cytoskeleton organization
GO:0030295 protein kinase activator activity
GO:0035014 phosphatidylinositol 3-kinase regulator activity
GO:0042177 negative regulation of protein catabolic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045860 positive regulation of protein kinase activity
GO:0046872 metal ion binding
GO:0061903 positive regulation of 1-phosphatidylinositol-3-kinase activity
GO:0070062 extracellular exosome
GO:0090543 Flemming body

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001164 Arf GTPase activating proteinDomainDomain
IPR001806 Small GTPaseFamilyFamily
IPR001849 Pleckstrin homology domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily

Diseases

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