Entity Details

Primary name TEP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99973
EntryNameTEP1_HUMAN
FullNameTelomerase protein component 1
TaxID9606
Evidenceevidence at protein level
Length2627
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesTEP1

GO terms

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GOName
GO:0000722 telomere maintenance via recombination
GO:0000781 chromosome, telomeric region
GO:0002039 p53 binding
GO:0003720 telomerase activity
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005697 telomerase holoenzyme complex
GO:0005737 cytoplasm
GO:0016363 nuclear matrix
GO:0019899 enzyme binding
GO:0070034 telomerase RNA binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR007111 NACHT nucleoside triphosphataseDomainDomain
IPR008850 TEP1, N-terminalRepeatRepeat
IPR008858 TROVE domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR025139 Domain of unknown function DUF4062DomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037214 TROVE domain superfamilyFamilyHomologous superfamily

Diseases

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