Entity Details

Primary name DHB14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BPX1
EntryNameDHB14_HUMAN
FullName17-beta-hydroxysteroid dehydrogenase 14
TaxID9606
Evidenceevidence at protein level
Length270
SequenceStatuscomplete
DateCreated2005-10-11
DateModified2021-06-02

Ontological Relatives

GenesHSD17B14

GO terms

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GOName
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005829 cytosol
GO:0006703 estrogen biosynthetic process
GO:0006706 steroid catabolic process
GO:0042802 identical protein binding
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

24 interactions

InteractorPartnerSourcesPublicationsLink
DHB14_HUMANDDIT3_HUMANBioGRID, HPRD, IntAct16189514 25416956 27107012 32296183 details
DHB14_HUMANNTAQ1_HUMANBioGRID, HPRD, IntAct16189514 19060904 25416956 27107012 31515488 32296183 details
DHB14_HUMANDHB14_HUMANBioGRID, HPRD, IntAct16189514 25416956 27107012 31515488 32296183 details
DHB14_HUMANNUD18_HUMANBioGRID, HPRD, IntAct16189514 19060904 details
DHB14_HUMANPSA1_HUMANBioGRID, IntAct19060904 31515488 details
DHB14_HUMANPHF1_HUMANBioGRID, IntAct25416956 31515488 32296183 details
DHB14_HUMAN3MG_HUMANBioGRID, IntAct25416956 25910212 31515488 details
DHB14_HUMANCAH8_HUMANBioGRID, IntAct25416956 25910212 27107012 31515488 32296183 details
DHB14_HUMANCDN2D_HUMANBioGRID, IntAct25416956 27107012 32296183 details
DHB14_HUMANSR1IP_HUMANBioGRID, IntAct25416956 31515488 details
DHB14_HUMANSNPC3_HUMANBioGRID, IntAct25416956 31515488 details
DHB14_HUMANDT3UO_HUMANIntAct25416956 details
DHB14_HUMANNEK6_HUMANBioGRID, IntAct25416956 32296183 details
DHB14_HUMANTB22B_HUMANBioGRID, IntAct25416956 29892012 32296183 details
DHB14_HUMANTGO1_HUMANBioGRID, IntAct27107012 details
DHB14_HUMANPICK1_HUMANBioGRID, IntAct32296183 details
DHB14_HUMANREL_HUMANBioGRID, IntAct32296183 details
DHB14_HUMANFANCJ_HUMANBioGRID, IntAct32296183 details
DHB14_HUMANPIDD1_HUMANBioGRID, IntAct32296183 details
DHB14_HUMANOTUD3_HUMANBioGRID, IntAct32296183 details
DHB14_HUMANAKIR2_HUMANBioGRID, IntAct32296183 details
DHB14_HUMANPGRP3_HUMANBioGRID, IntAct32296183 details
DHB14_HUMANRU1C_HUMANBioGRID, IntAct25416956 32296183 details
DHB14_HUMANINCA1_HUMANBioGRID, IntAct32296183 details