Entity Details

Primary name PD1L2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BQ51
EntryNamePD1L2_HUMAN
FullNameProgrammed cell death 1 ligand 2
TaxID9606
Evidenceevidence at protein level
Length273
SequenceStatuscomplete
DateCreated2005-05-10
DateModified2021-06-02

Ontological Relatives

GenesPDCD1LG2

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
GO:0031295 T cell costimulation
GO:0032689 negative regulation of interferon-gamma production
GO:0032693 negative regulation of interleukin-10 production
GO:0042102 positive regulation of T cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0046007 negative regulation of activated T cell proliferation
GO:0071222 cellular response to lipopolysaccharide

Subcellular Location

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Subcellular Location
Cell membrane
Endomembrane system
Secreted

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013162 CD80-like, immunoglobulin C2-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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