Entity Details

Primary name FUT8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BYC5
EntryNameFUT8_HUMAN
FullNameAlpha-(1,6)-fucosyltransferase
TaxID9606
Evidenceevidence at protein level
Length575
SequenceStatuscomplete
DateCreated2002-03-05
DateModified2021-06-02

Ontological Relatives

GenesFUT8

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001701 in utero embryonic development
GO:0005794 Golgi apparatus
GO:0006487 protein N-linked glycosylation
GO:0006491 N-glycan processing
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity
GO:0009312 oligosaccharide biosynthetic process
GO:0010468 regulation of gene expression
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0017124 SH3 domain binding
GO:0018279 protein N-linked glycosylation via asparagine
GO:0019082 viral protein processing
GO:0032580 Golgi cisterna membrane
GO:0033578 protein glycosylation in Golgi
GO:0036071 N-glycan fucosylation
GO:0042355 L-fucose catabolic process
GO:0043112 receptor metabolic process
GO:0046368 GDP-L-fucose metabolic process
GO:0046921 alpha-(1->6)-fucosyltransferase activity
GO:0070062 extracellular exosome
GO:1900407 regulation of cellular response to oxidative stress

Subcellular Location

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Subcellular Location
Golgi apparatus

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR015827 Alpha-(1,6)-fucosyltransferaseFamilyFamily
IPR027350 Glycosyltransferase family 23 (GT23) domainDomainDomain
IPR035653 Alpha-(1,6)-fucosyltransferase, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
FUT8_HUMANZBT10_HUMANBioGRID, IntAct32296183 details
FUT8_HUMANFBX7_HUMANBioGRID27503909 details
FUT8_HUMANTM258_HUMANBioGRID26472760 details