Entity Details

Primary name FGF23_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9GZV9
EntryNameFGF23_HUMAN
FullNameFibroblast growth factor 23
TaxID9606
Evidenceevidence at protein level
Length251
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesFGF23

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005105 type 1 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
GO:0005796 Golgi lumen
GO:0006796 phosphate-containing compound metabolic process
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0010966 regulation of phosphate transport
GO:0010980 positive regulation of vitamin D 24-hydroxylase activity
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0030502 negative regulation of bone mineralization
GO:0030643 cellular phosphate ion homeostasis
GO:0032026 response to magnesium ion
GO:0042369 vitamin D catabolic process
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044320 cellular response to leptin stimulus
GO:0045668 negative regulation of osteoblast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046888 negative regulation of hormone secretion
GO:0051897 positive regulation of protein kinase B signaling
GO:0055062 phosphate ion homeostasis
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071305 cellular response to vitamin D
GO:0071354 cellular response to interleukin-6
GO:0071374 cellular response to parathyroid hormone stimulus
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:1904383 response to sodium phosphate

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028304 Fibroblast growth factor 23FamilyFamily

Diseases

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