Entity Details

Primary name FOXP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H334
EntryNameFOXP1_HUMAN
FullNameForkhead box protein P1
TaxID9606
Evidenceevidence at protein level
Length677
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesFOXP1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001046 core promoter sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0002903 negative regulation of B cell apoptotic process
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006974 cellular response to DNA damage stimulus
GO:0010468 regulation of gene expression
GO:0010595 positive regulation of endothelial cell migration
GO:0010629 negative regulation of gene expression
GO:0030316 osteoclast differentiation
GO:0032496 response to lipopolysaccharide
GO:0032651 regulation of interleukin-1 beta production
GO:0032655 regulation of interleukin-12 production
GO:0032680 regulation of tumor necrosis factor production
GO:0032745 positive regulation of interleukin-21 production
GO:0035019 somatic stem cell population maintenance
GO:0036035 osteoclast development
GO:0042116 macrophage activation
GO:0042117 monocyte activation
GO:0042118 endothelial cell activation
GO:0043621 protein self-association
GO:0045655 regulation of monocyte differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050681 androgen receptor binding
GO:0050727 regulation of inflammatory response
GO:0050861 positive regulation of B cell receptor signaling pathway
GO:0060766 negative regulation of androgen receptor signaling pathway
GO:0061470 T follicular helper cell differentiation
GO:1900424 regulation of defense response to bacterium
GO:1901256 regulation of macrophage colony-stimulating factor production
GO:1901509 regulation of endothelial tube morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR032354 FOXP, coiled-coil domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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