Entity Details

Primary name AT132_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NQ11
EntryNameAT132_HUMAN
FullNamePolyamine-transporting ATPase 13A2
TaxID9606
Evidenceevidence at protein level
Length1180
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesATP13A2

GO terms

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GOName
GO:0000421 autophagosome membrane
GO:0005524 ATP binding
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0005771 multivesicular body
GO:0005776 autophagosome
GO:0006874 cellular calcium ion homeostasis
GO:0006879 cellular iron ion homeostasis
GO:0006882 cellular zinc ion homeostasis
GO:0006914 autophagy
GO:0007041 lysosomal transport
GO:0008270 zinc ion binding
GO:0010628 positive regulation of gene expression
GO:0010821 regulation of mitochondrion organization
GO:0012506 vesicle membrane
GO:0015417 ABC-type polyamine transporter activity
GO:0016021 integral component of membrane
GO:0016241 regulation of macroautophagy
GO:0016243 regulation of autophagosome size
GO:0016887 ATP hydrolysis activity
GO:0019829 ATPase-coupled cation transmembrane transporter activity
GO:0030003 cellular cation homeostasis
GO:0030133 transport vesicle
GO:0030145 manganese ion binding
GO:0031982 vesicle
GO:0032585 multivesicular body membrane
GO:0033157 regulation of intracellular protein transport
GO:0034220 ion transmembrane transport
GO:0034599 cellular response to oxidative stress
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043202 lysosomal lumen
GO:0046777 protein autophosphorylation
GO:0050714 positive regulation of protein secretion
GO:0052548 regulation of endopeptidase activity
GO:0055069 zinc ion homeostasis
GO:0055088 lipid homeostasis
GO:0061462 protein localization to lysosome
GO:0061909 autophagosome-lysosome fusion
GO:0070300 phosphatidic acid binding
GO:0071287 cellular response to manganese ion
GO:0071294 cellular response to zinc ion
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
GO:0097734 extracellular exosome biogenesis
GO:1900180 regulation of protein localization to nucleus
GO:1901215 negative regulation of neuron death
GO:1902047 polyamine transmembrane transport
GO:1903135 cupric ion binding
GO:1903146 regulation of autophagy of mitochondrion
GO:1903543 positive regulation of exosomal secretion
GO:1903710 spermine transmembrane transport
GO:1904714 regulation of chaperone-mediated autophagy
GO:1905037 autophagosome organization
GO:1905103 integral component of lysosomal membrane
GO:1905123 regulation of glucosylceramidase activity
GO:1905165 regulation of lysosomal protein catabolic process
GO:1905166 negative regulation of lysosomal protein catabolic process
GO:1990938 peptidyl-aspartic acid autophosphorylation
GO:2000152 regulation of ubiquitin-specific protease activity

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Endosome
Late endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR006544 P-type ATPase, subfamily VFamilyFamily
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
AT132_HUMANCKLF6_HUMANBioGRID, MINT21900206 details
AT132_HUMANACTB_HUMANIntAct22645275 details
AT132_HUMANSC61B_HUMANBioGRID, IntAct22645275 details
AT132_HUMANPDIA6_HUMANBioGRID, IntAct22645275 details
AT132_HUMANASTER_HUMANBioGRID, IntAct22645275 details
AT132_HUMANDCAF7_HUMANBioGRID, IntAct22645275 details
AT132_HUMANHIPK1_HUMANBioGRID, IntAct22645275 details
AT132_HUMANLRP6_HUMANBioGRID, IntAct22645275 details
AT132_HUMANICAM2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANGPR21_HUMANBioGRID, IntAct22645275 details
AT132_HUMANP_HUMANBioGRID, IntAct22645275 details
AT132_HUMANAT5G2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANBNI3L_HUMANBioGRID, IntAct22645275 details
AT132_HUMANHDAC6_HUMANBioGRID, IntAct22645275 details
AT132_HUMANVAMP2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANNPY1R_HUMANBioGRID, IntAct22645275 details
AT132_HUMANLMAN2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANEMC7_HUMANBioGRID, IntAct22645275 details
AT132_HUMANHSP7C_HUMANBioGRID, IntAct22645275 details
AT132_HUMANFUND2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANSPCS2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANAAK1_HUMANBioGRID, IntAct22645275 details
AT132_HUMANFA8A1_HUMANBioGRID, IntAct22645275 details
AT132_HUMANGAK_HUMANBioGRID, IntAct22645275 details
AT132_HUMANF111B_HUMANBioGRID, IntAct22645275 details
AT132_HUMANUB2J2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANPCMD2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANOSTC_HUMANBioGRID, IntAct22645275 details
AT132_HUMANFKBP8_HUMANBioGRID, IntAct22645275 details
AT132_HUMANCXCR4_HUMANBioGRID, IntAct22645275 details
AT132_HUMANYIF1A_HUMANBioGRID, IntAct22645275 details
AT132_HUMANMYCB2_HUMANBioGRID, IntAct22645275 details
AT132_HUMANACKR3_HUMANBioGRID, IntAct22645275 details
AT132_HUMANPIP30_HUMANBioGRID, IntAct22645275 details
AT132_HUMANCO1A1_HUMANBioGRID, IntAct22645275 details
AT132_HUMANWDR5B_HUMANBioGRID, IntAct22645275 details
AT132_HUMANCYGB_HUMANBioGRID, IntAct22645275 details
AT132_HUMANMEX3B_HUMANBioGRID, IntAct22645275 details
AT132_HUMANTSN14_HUMANBioGRID, IntAct22645275 details
AT132_HUMANGASR_HUMANBioGRID, IntAct22645275 details
AT132_HUMANPCDBA_HUMANBioGRID, IntAct22645275 details
AT132_HUMANSYT11_HUMANBioGRID, IntAct22645275 details
AT132_HUMANPAR1_HUMANBioGRID, IntAct22645275 details
AT132_HUMANNRX1B_HUMANBioGRID22645275 details
AT132_HUMANNRX1A_HUMANBioGRID22645275 details
AT132_HUMANLAMP1_HUMANBioGRID22768177 details
AT132_HUMANRAB5A_HUMANBioGRID22768177 details
AT132_HUMANRAB7A_HUMANBioGRID22768177 details
AT132_HUMANRAB9A_HUMANBioGRID22768177 details