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Entity Details
Primary name
DPOE3_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9NRF9
EntryName
DPOE3_HUMAN
FullName
DNA polymerase epsilon subunit 3
TaxID
9606
Evidence
evidence at protein level
Length
147
SequenceStatus
complete
DateCreated
2002-08-30
DateModified
2021-06-02
Ontological Relatives
Genes
POLE3
GO terms
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GO
Name
GO:0003887
DNA-directed DNA polymerase activity
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005671
Ada2/Gcn5/Ada3 transcription activator complex
GO:0006260
DNA replication
GO:0006270
DNA replication initiation
GO:0006272
leading strand elongation
GO:0006974
cellular response to DNA damage stimulus
GO:0008622
epsilon DNA polymerase complex
GO:0008623
CHRAC
GO:0031490
chromatin DNA binding
GO:0031507
heterochromatin assembly
GO:0042766
nucleosome mobilization
GO:0043966
histone H3 acetylation
GO:0046982
protein heterodimerization activity
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR003958
Transcription factor CBF/NF-Y/archaeal histone domain
Domain
Domain
IPR009072
Histone-fold
Family
Homologous superfamily
Diseases
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Drugs
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Drug
Name
Source
Type
DB00242
Cladribine
Drugbank
small molecule
Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
DPOE3_HUMAN
NC2A_HUMAN
BioGRID, HPRD, IntAct
16189514
25416956
32296183
details
DPOE3_HUMAN
NC2B_HUMAN
BioGRID, HPRD, IntAct
16189514
25416956
31515488
32296183
details
DPOE3_HUMAN
DPOE4_HUMAN
BioGRID, HPRD, IntAct
10801849
22939629
26344197
32296183
details
DPOE3_HUMAN
DPOE1_HUMAN
BioGRID, IntAct
10801849
21705323
22939629
26344197
27235625
details
DPOE3_HUMAN
DPOE2_HUMAN
BioGRID, IntAct
10801849
21705323
28514442
details
DPOE3_HUMAN
CHRC1_HUMAN
BioGRID, HPRD, IntAct, MINT
10880450
21516116
25416956
26344197
32296183
details
DPOE3_HUMAN
SMCA5_HUMAN
BioGRID
10880450
14759371
26344197
details
DPOE3_HUMAN
BAZ1A_HUMAN
BioGRID
10880450
14759371
details
DPOE3_HUMAN
A4_HUMAN
BioGRID
21832049
details
DPOE3_HUMAN
RAD17_HUMAN
BioGRID
14500819
details
DPOE3_HUMAN
XRCC5_HUMAN
BioGRID
21172662
details
DPOE3_HUMAN
YETS2_HUMAN
BioGRID
18838386
details
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