Entity Details

Primary name GLRX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NS18
EntryNameGLRX2_HUMAN
FullNameGlutaredoxin-2, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length164
SequenceStatuscomplete
DateCreated2005-08-30
DateModified2021-06-02

Ontological Relatives

GenesGLRX2

GO terms

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GOName
GO:0003756 protein disulfide isomerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006355 regulation of transcription, DNA-templated
GO:0006749 glutathione metabolic process
GO:0006915 apoptotic process
GO:0007568 aging
GO:0008794 arsenate reductase (glutaredoxin) activity
GO:0009055 electron transfer activity
GO:0009266 response to temperature stimulus
GO:0009966 regulation of signal transduction
GO:0010033 response to organic substance
GO:0015035 protein-disulfide reductase activity
GO:0015038 glutathione disulfide oxidoreductase activity
GO:0030154 cell differentiation
GO:0030425 dendrite
GO:0042262 DNA protection
GO:0042542 response to hydrogen peroxide
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
GO:0045454 cell redox homeostasis
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051775 response to redox state
GO:0071451 cellular response to superoxide

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR002109 GlutaredoxinDomainDomain
IPR011899 Glutaredoxin, eukaryotic/virialDomainDomain
IPR014025 Glutaredoxin subgroupDomainDomain
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
GLRX2_HUMANDCXR_HUMANBioGRID, IntAct32296183 details
GLRX2_HUMANELF5_HUMANBioGRID, IntAct32296183 details
GLRX2_HUMANTRXR1_HUMANBioGRID, HPRD14676218 details
GLRX2_HUMANFBX7_HUMANBioGRID27503909 details