Entity Details

Primary name IL37_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZH6
EntryNameIL37_HUMAN
FullNameInterleukin-37
TaxID9606
Evidenceevidence at protein level
Length218
SequenceStatuscomplete
DateCreated2002-11-08
DateModified2021-06-02

Ontological Relatives

GenesIL37

GO terms

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GOName
GO:0002437 inflammatory response to antigenic stimulus
GO:0005125 cytokine activity
GO:0005149 interleukin-1 receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0010628 positive regulation of gene expression
GO:0019221 cytokine-mediated signaling pathway
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0043231 intracellular membrane-bounded organelle
GO:0050727 regulation of inflammatory response
GO:0071222 cellular response to lipopolysaccharide
GO:0071345 cellular response to cytokine stimulus

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR000975 Interleukin-1 familyFamilyFamily
IPR003297 Interleukin-1 receptor antagonist/Interleukin-36FamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily

Diseases

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