Entity Details

Primary name APC5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UJX4
EntryNameAPC5_HUMAN
FullNameAnaphase-promoting complex subunit 5
TaxID9606
Evidenceevidence at protein level
Length755
SequenceStatuscomplete
DateCreated2003-10-03
DateModified2021-06-02

Ontological Relatives

GenesANAPC5

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005680 anaphase-promoting complex
GO:0005819 spindle
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007049 cell cycle
GO:0007096 regulation of exit from mitosis
GO:0019903 protein phosphatase binding
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0051301 cell division
GO:0070979 protein K11-linked ubiquitination
GO:1901990 regulation of mitotic cell cycle phase transition

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR019734 Tetratricopeptide repeatRepeatRepeat
IPR026000 Anaphase-promoting complex subunit 5 domainDomainDomain
IPR037679 Anaphase-promoting complex subunit 5FamilyFamily

Diseases

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Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
APC5_HUMANZBT16_HUMANBioGRID, HPRD, IntAct16169070 details
APC5_HUMANBACH1_HUMANBioGRID, IntAct21988832 details
APC5_HUMANMK06_HUMANBioGRID, MINT21900206 details
APC5_HUMANFZR1_HUMANBioGRID, IntAct12956947 23160376 28514442 details
APC5_HUMANPABP1_HUMANBioGRID, HPRD15082755 details
APC5_HUMANCBP_HUMANBioGRID16319895 details
APC5_HUMANFBX5_HUMANBioGRID16921029 details
APC5_HUMANUBE2S_HUMANBioGRID25306923 details
APC5_HUMANCDC27_HUMANBioGRID, IntAct10922056 12956947 14657031 15082755 16364912 20360068 20686030 21043528 21241890 22193957 22792066 22939629 25306918 26811472 27114510 32076268 32152539 details
APC5_HUMANAPC1_HUMANBioGRID, IntAct11076961 12956947 20360068 22939629 26344197 details
APC5_HUMANCDC20_HUMANBioGRID, IntAct20360068 23160376 25306918 26811472 27114510 details
APC5_HUMANAPC7_HUMANBioGRID, IntAct20360068 22939629 23160376 details
APC5_HUMANAPC4_HUMANBioGRID, DIP, IntAct12956947 20360068 22939629 23078409 25043029 25490258 26083744 26344197 29549242 details
APC5_HUMANANC2_HUMANBioGRID, DIP, IntAct10922056 12956947 20360068 22939629 25043029 26083744 27120157 34079125 details
APC5_HUMANAPC15_HUMANBioGRID, IntAct23007861 26496610 details
APC5_HUMANCDT1_HUMANBioGRID18162579 details
APC5_HUMANEP300_HUMANBioGRID16319895 details
APC5_HUMANMDC1_HUMANBioGRID17827148 22990118 details
APC5_HUMANSMRCD_HUMANBioGRID21549307 details
APC5_HUMANE2F1_HUMANBioGRID22580462 25368385 details
APC5_HUMANSH3K1_HUMANBioGRID19531213 details
APC5_HUMANUBP37_HUMANBioGRID21596315 26299517 details
APC5_HUMANTRI33_HUMANBioGRID23160376 details
APC5_HUMANPHF8_HUMANBioGRID23979597 details
APC5_HUMANLATS2_HUMANBioGRID24255178 29183995 details
APC5_HUMANTFDP1_HUMANBioGRID25368385 details
APC5_HUMANSMUF1_HUMANHPRD15761153 details
APC5_HUMANSMUF2_HUMANHPRD15761153 details
APC5_HUMANTGFR1_HUMANHPRD15761153 details