Entity Details

Primary name JAG2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y219
EntryNameJAG2_HUMAN
FullNameProtein jagged-2
TaxID9606
Evidenceevidence at protein level
Length1238
SequenceStatuscomplete
DateCreated2002-03-27
DateModified2021-06-02

Ontological Relatives

GenesJAG2

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001701 in utero embryonic development
GO:0003016 respiratory system process
GO:0005112 Notch binding
GO:0005509 calcium ion binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007219 Notch signaling pathway
GO:0007283 spermatogenesis
GO:0008083 growth factor activity
GO:0009912 auditory receptor cell fate commitment
GO:0016331 morphogenesis of embryonic epithelium
GO:0030154 cell differentiation
GO:0030155 regulation of cell adhesion
GO:0030217 T cell differentiation
GO:0042127 regulation of cell population proliferation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042492 gamma-delta T cell differentiation
GO:0045061 thymic T cell selection
GO:0045747 positive regulation of Notch signaling pathway
GO:1990134 epithelial cell apoptotic process involved in palatal shelf morphogenesis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001007 VWFC domainDomainDomain
IPR001774 Delta/Serrate/lag-2 (DSL) proteinDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011651 Notch ligand, N-terminal domainDomainDomain
IPR013032 EGF-like, conserved siteSiteConserved site
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR026219 Jagged/Serrate proteinFamilyFamily

Diseases

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