Entity Details

Primary name RTCB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y3I0
EntryNameRTCB_HUMAN
FullNameRNA-splicing ligase RtcB homolog
TaxID9606
Evidenceevidence at protein level
Length505
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesRTCB

GO terms

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GOName
GO:0000971 tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate
GO:0003723 RNA binding
GO:0003972 RNA ligase (ATP) activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0017166 vinculin binding
GO:0043231 intracellular membrane-bounded organelle
GO:0046872 metal ion binding
GO:0072669 tRNA-splicing ligase complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001233 RNA-splicing ligase, RtcBFamilyFamily
IPR027513 RNA-splicing ligase RtcB homologue, eukaryoticFamilyFamily
IPR036025 tRNA-splicing ligase RtcB-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02772 SucroseDrugbanksmall molecule

Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
RTCB_HUMANCRK_HUMANBioGRID, IntAct25814554 details
RTCB_HUMANDP13A_HUMANBioGRID, IntAct25814554 details
RTCB_HUMANESR1_HUMANBioGRID, IntAct20348541 31527615 details
RTCB_HUMANOGT1_HUMANBioGRID32994395 details
RTCB_HUMAN1433Z_HUMANMINT15161933 details
RTCB_HUMANMTA2_HUMANBioGRID, IntAct27173435 unassigned1312 details
RTCB_HUMANHDAC1_HUMANBioGRID, IntAct27173435 unassigned1312 details
RTCB_HUMANXYLT2_HUMANBioGRID, IntAct27173435 unassigned1312 details
RTCB_HUMANDDX1_HUMANBioGRID, IntAct, UniProt22863883 22939629 24608264 24981860 26344197 27173435 29395067 30833792 unassigned1312 details
RTCB_HUMANPTOV1_HUMANBioGRID, IntAct27173435 unassigned1312 details
RTCB_HUMANRFX3_HUMANBioGRID, IntAct27173435 unassigned1312 details
RTCB_HUMANARCH_HUMANDIP24870230 details
RTCB_HUMANRTRAF_HUMANBioGRID, IntAct, UniProt22863883 22939629 24608264 24981860 26344197 30833792 details
RTCB_HUMANCAH9_HUMANBioGRID23181366 details
RTCB_HUMANAICDA_HUMANBioGRID23277564 details
RTCB_HUMANFXR2_HUMANBioGRID29395067 details
RTCB_HUMANMEX3B_HUMANBioGRID29395067 details
RTCB_HUMANNUFP2_HUMANBioGRID29395067 details
RTCB_HUMANTDRD3_HUMANBioGRID29395067 details
RTCB_HUMANUBP2L_HUMANBioGRID29395067 details
RTCB_HUMANYTHD2_HUMANBioGRID29395067 details
RTCB_HUMANYTHD3_HUMANBioGRID29395067 details
RTCB_HUMANDDX3X_HUMANBioGRID29395067 details
RTCB_HUMANLAR4B_HUMANBioGRID29395067 details
RTCB_HUMANRBMS1_HUMANBioGRID29395067 details
RTCB_HUMANPABP1_HUMANBioGRID29395067 details