Entity Details

Primary name KLF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5W3
EntryNameKLF2_HUMAN
FullNameKrueppel-like factor 2
TaxID9606
Evidenceevidence at protein level
Length355
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesKLF2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000902 cell morphogenesis
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001701 in utero embryonic development
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0032715 negative regulation of interleukin-6 production
GO:0035264 multicellular organism growth
GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0040029 regulation of gene expression, epigenetic
GO:0042311 vasodilation
GO:0043249 erythrocyte maturation
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048386 positive regulation of retinoic acid receptor signaling pathway
GO:0051247 positive regulation of protein metabolic process
GO:0060509 type I pneumocyte differentiation
GO:0070301 cellular response to hydrogen peroxide
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071409 cellular response to cycloheximide
GO:0071498 cellular response to fluid shear stress
GO:0071499 cellular response to laminar fluid shear stress
GO:0097533 cellular stress response to acid chemical
GO:1901653 cellular response to peptide
GO:1903671 negative regulation of sprouting angiogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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