Entity Details

Primary name FCSD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94868
EntryNameFCSD2_HUMAN
FullNameF-BAR and double SH3 domains protein 2
TaxID9606
Evidenceevidence at protein level
Length740
SequenceStatuscomplete
DateCreated2007-02-20
DateModified2021-06-02

Ontological Relatives

GenesFCHSD2

GO terms

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GOName
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0007274 neuromuscular synaptic transmission
GO:0015031 protein transport
GO:0030833 regulation of actin filament polymerization
GO:0030838 positive regulation of actin filament polymerization
GO:0031594 neuromuscular junction
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0055037 recycling endosome
GO:0072583 clathrin-dependent endocytosis
GO:0120043 stereocilium shaft
GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR001060 FCH domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR031160 F-BAR domainDomainDomain
IPR034934 F-BAR and double SH3 domains protein 2FamilyFamily
IPR035460 FCHSD, SH3 domain 1DomainDomain
IPR035556 FCHSD2, SH3 domain 2DomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

60 interactions

InteractorPartnerSourcesPublicationsLink
FCSD2_HUMANCD158_HUMANBioGRID, HPRD, IntAct16189514 details
FCSD2_HUMANCC85B_HUMANBioGRID, HPRD, IntAct16189514 details
FCSD2_HUMANMAGI1_HUMANBioGRID, IntAct14627983 28514442 details
FCSD2_HUMANTERA_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANBIP_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANVCIP1_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANCFA36_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANSRP72_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANCB073_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANMSL1_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANSH3BG_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANTCPB_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANCHKA_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANHS90B_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANTLS1_HUMANBioGRID, IntAct18654987 details
FCSD2_HUMANMTUS2_HUMANBioGRID, IntAct, MINT21516116 25416956 31515488 details
FCSD2_HUMANWASP_HUMANBioGRID, IntAct21988832 details
FCSD2_HUMANWASL_HUMANBioGRID, IntAct21988832 details
FCSD2_HUMANDAPP1_HUMANBioGRID, IntAct21988832 details
FCSD2_HUMANFAM9B_HUMANBioGRID, IntAct25416956 31515488 details
FCSD2_HUMANKIFC3_HUMANBioGRID, IntAct25416956 details
FCSD2_HUMANABCF3_HUMANBioGRID, IntAct25416956 31515488 details
FCSD2_HUMANHGS_HUMANBioGRID, IntAct26871637 details
FCSD2_HUMANCTG1B_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANBORC6_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANGASP2_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANLDOC1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANCDK18_HUMANIntAct32296183 details
FCSD2_HUMANMFAP1_HUMANIntAct32296183 details
FCSD2_HUMANCCHCR_HUMANIntAct32296183 details
FCSD2_HUMANMNS1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANATPF2_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANSAS6_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANHOME1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANCC120_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANKAP1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANACAP1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANZN587_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANSH24A_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANUSBP1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANSRTD3_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANRINT1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANVP37C_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANENKD1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANMOFA1_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANLCA5L_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANHDAC4_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANT10IP_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANTLE5_HUMANBioGRID, IntAct32296183 details
FCSD2_HUMANFGFR3_HUMANIntAct32814053 details
FCSD2_HUMANGELS_HUMANIntAct32814053 details
FCSD2_HUMANRASH_HUMANIntAct32814053 details
FCSD2_HUMANCSKP_HUMANBioGRID, HPRD14627983 details
FCSD2_HUMANITSN1_HUMANBioGRID22558309 details
FCSD2_HUMANITSN2_HUMANBioGRID22558309 details
FCSD2_HUMANMYOME_HUMANBioGRID25416956 details
FCSD2_HUMANFCSD2_HUMANBioGRID26702831 details
FCSD2_HUMANANS1A_HUMANBioGRID32296183 details
FCSD2_HUMANCC183_HUMANBioGRID32296183 details
FCSD2_HUMANHTRA1_HUMANHPRD15101818 details