Entity Details

Primary name ABCA8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94911
EntryNameABCA8_HUMAN
FullNameABC-type organic anion transporter ABCA8
TaxID9606
Evidenceevidence at protein level
Length1621
SequenceStatuscomplete
DateCreated2006-10-03
DateModified2021-06-02

Ontological Relatives

GenesABCA8

GO terms

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GOName
GO:0005319 lipid transporter activity
GO:0005524 ATP binding
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006686 sphingomyelin biosynthetic process
GO:0006869 lipid transport
GO:0008559 ABC-type xenobiotic transporter activity
GO:0010874 regulation of cholesterol efflux
GO:0010875 positive regulation of cholesterol efflux
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0030301 cholesterol transport
GO:0033344 cholesterol efflux
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042908 xenobiotic transport
GO:0043231 intracellular membrane-bounded organelle
GO:0055085 transmembrane transport
GO:0140359 ABC-type transporter activity

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR026082 ABC transporter AFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030372 ABC-type organic anion transporter ABCA8FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ABCA8_HUMANDISC1_HUMANIntAct31413325 details