Entity Details

Primary name INHBA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08476
EntryNameINHBA_HUMAN
FullNameInhibin beta A chain
TaxID9606
Evidenceevidence at protein level
Length426
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesINHBA

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001541 ovarian follicle development
GO:0001942 hair follicle development
GO:0002244 hematopoietic progenitor cell differentiation
GO:0005125 cytokine activity
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006952 defense response
GO:0007166 cell surface receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007399 nervous system development
GO:0008083 growth factor activity
GO:0008285 negative regulation of cell population proliferation
GO:0008584 male gonad development
GO:0010628 positive regulation of gene expression
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0017046 peptide hormone binding
GO:0021773 striatal medium spiny neuron differentiation
GO:0030154 cell differentiation
GO:0030218 erythrocyte differentiation
GO:0030308 negative regulation of cell growth
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032689 negative regulation of interferon-gamma production
GO:0032924 activin receptor signaling pathway
GO:0034711 inhibin binding
GO:0035987 endodermal cell differentiation
GO:0042326 negative regulation of phosphorylation
GO:0042476 odontogenesis
GO:0042493 response to drug
GO:0042541 hemoglobin biosynthetic process
GO:0042701 progesterone secretion
GO:0042802 identical protein binding
GO:0043509 activin A complex
GO:0043512 inhibin A complex
GO:0044877 protein-containing complex binding
GO:0045578 negative regulation of B cell differentiation
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045650 negative regulation of macrophage differentiation
GO:0045786 negative regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046880 regulation of follicle-stimulating hormone secretion
GO:0046881 positive regulation of follicle-stimulating hormone secretion
GO:0046882 negative regulation of follicle-stimulating hormone secretion
GO:0048333 mesodermal cell differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0060021 roof of mouth development
GO:0060279 positive regulation of ovulation
GO:0060395 SMAD protein signal transduction
GO:0061029 eyelid development in camera-type eye
GO:0070699 type II activin receptor binding
GO:0071372 cellular response to follicle-stimulating hormone stimulus
GO:0071397 cellular response to cholesterol
GO:0097154 GABAergic neuron differentiation
GO:0097191 extrinsic apoptotic signaling pathway
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000491 Inhibin, beta A subunitFamilyFamily
IPR001111 TGF-beta, propeptideDomainDomain
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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