Entity Details

Primary name VILI_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09327
EntryNameVILI_HUMAN
FullNameVillin-1
TaxID9606
Evidenceevidence at protein level
Length827
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesVIL1

GO terms

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GOName
GO:0001726 ruffle
GO:0001951 intestinal D-glucose absorption
GO:0005509 calcium ion binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005903 brush border
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0008154 actin polymerization or depolymerization
GO:0008360 regulation of cell shape
GO:0009617 response to bacterium
GO:0010634 positive regulation of epithelial cell migration
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0030041 actin filament polymerization
GO:0030042 actin filament depolymerization
GO:0030175 filopodium
GO:0030335 positive regulation of cell migration
GO:0030836 positive regulation of actin filament depolymerization
GO:0030855 epithelial cell differentiation
GO:0032233 positive regulation of actin filament bundle assembly
GO:0032432 actin filament bundle
GO:0032433 filopodium tip
GO:0032532 regulation of microvillus length
GO:0035727 lysophosphatidic acid binding
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0040018 positive regulation of multicellular organism growth
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0045010 actin nucleation
GO:0051014 actin filament severing
GO:0051015 actin filament binding
GO:0051016 barbed-end actin filament capping
GO:0051125 regulation of actin nucleation
GO:0051693 actin filament capping
GO:0060327 cytoplasmic actin-based contraction involved in cell motility
GO:0061041 regulation of wound healing
GO:0065003 protein-containing complex assembly
GO:0070062 extracellular exosome
GO:0071364 cellular response to epidermal growth factor stimulus
GO:1902896 terminal web assembly
GO:1903078 positive regulation of protein localization to plasma membrane
GO:2000392 regulation of lamellipodium morphogenesis
GO:2000394 positive regulation of lamellipodium morphogenesis

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR003128 Villin headpieceDomainDomain
IPR007122 Villin/GelsolinFamilyFamily
IPR007123 Gelsolin-like domainDomainDomain
IPR029006 ADF-H/Gelsolin-like domain superfamilyFamilyHomologous superfamily
IPR030007 Villin-1FamilyFamily
IPR036180 Gelsolin-like domain superfamilyFamilyHomologous superfamily
IPR036886 Villin headpiece domain superfamilyFamilyHomologous superfamily

Diseases

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