Entity Details

Primary name CMGA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10645
EntryNameCMGA_HUMAN
FullNameChromogranin-A
TaxID9606
Evidenceevidence at protein level
Length457
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesCHGA

GO terms

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GOName
GO:0002026 regulation of the force of heart contraction
GO:0002551 mast cell chemotaxis
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006996 organelle organization
GO:0008217 regulation of blood pressure
GO:0019730 antimicrobial humoral response
GO:0030133 transport vesicle
GO:0030141 secretory granule
GO:0031640 killing of cells of other organism
GO:0033366 protein localization to secretory granule
GO:0033604 negative regulation of catecholamine secretion
GO:0042583 chromaffin granule
GO:0042742 defense response to bacterium
GO:0043303 mast cell degranulation
GO:0045087 innate immune response
GO:0045576 mast cell activation
GO:0046676 negative regulation of insulin secretion
GO:0048471 perinuclear region of cytoplasm
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0050832 defense response to fungus
GO:0060452 positive regulation of cardiac muscle contraction
GO:0086030 adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation
GO:0098992 neuronal dense core vesicle
GO:1900738 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
GO:1901215 negative regulation of neuron death
GO:1901899 positive regulation of relaxation of cardiac muscle
GO:2000707 positive regulation of dense core granule biogenesis

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Secreted

Domains

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DomainNameCategoryType
IPR001819 Chromogranin A/BFamilyFamily
IPR001990 Chromogranin A/B/CFamilyFamily
IPR018054 Chromogranin, conserved siteSiteConserved site

Diseases

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