Entity Details

Primary name IL7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13232
EntryNameIL7_HUMAN
FullNameInterleukin-7
TaxID9606
Evidenceevidence at protein level
Length177
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesIL7

GO terms

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GOName
GO:0001961 positive regulation of cytokine-mediated signaling pathway
GO:0002360 T cell lineage commitment
GO:0005125 cytokine activity
GO:0005139 interleukin-7 receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006959 humoral immune response
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0009887 animal organ morphogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0030890 positive regulation of B cell proliferation
GO:0032722 positive regulation of chemokine production
GO:0038111 interleukin-7-mediated signaling pathway
GO:0043066 negative regulation of apoptotic process
GO:0043086 negative regulation of catalytic activity
GO:0045453 bone resorption
GO:0045579 positive regulation of B cell differentiation
GO:0045582 positive regulation of T cell differentiation
GO:0046622 positive regulation of organ growth
GO:0048873 homeostasis of number of cells within a tissue
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0062023 collagen-containing extracellular matrix
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001181 Interleukin-7FamilyFamily
IPR018049 Interleukin-7/Interleukin-9, conserved siteSiteConserved site
IPR038325 Interleukin-7 superfamilyFamilyHomologous superfamily

Diseases

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