Entity Details

Primary name NQO2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP16083
EntryNameNQO2_HUMAN
FullNameRibosyldihydronicotinamide dehydrogenase [quinone]
TaxID9606
Evidenceevidence at protein level
Length231
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesNQO2

GO terms

Show/Hide Table
GOName
GO:0001512 dihydronicotinamide riboside quinone reductase activity
GO:0003955 NAD(P)H dehydrogenase (quinone) activity
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006805 xenobiotic metabolic process
GO:0007613 memory
GO:0008270 zinc ion binding
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors
GO:0031404 chloride ion binding
GO:0042803 protein homodimerization activity
GO:0043525 positive regulation of neuron apoptotic process
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071949 FAD binding
GO:1901662 quinone catabolic process
GO:1904408 melatonin binding
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1905594 resveratrol binding
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR003680 Flavodoxin-like foldDomainDomain
IPR029039 Flavoprotein-like superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00170 MenadioneDrugbanksmall molecule
DB01065 MelatoninDrugbanksmall molecule
DB01087 PrimaquineDrugbanksmall molecule
DB02709 ResveratrolDrugbanksmall molecule
DB03147 Flavin adenine dinucleotideDrugbanksmall molecule
DB03541 10-Propargyl-5,8-Dideazafolic AcidDrugbanksmall molecule
DB04216 QuercetinDrugbanksmall molecule
DB04253 TretazicarDrugbanksmall molecule
DB06695 Dabigatran etexilateDrugbanksmall molecule
DB07339 (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dioneDrugbanksmall molecule
DB08190 N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamideDrugbanksmall molecule
DB08228 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-oneDrugbanksmall molecule
DB08744 CasimiroinDrugbanksmall molecule