Entity Details

Primary name TYRP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17643
EntryNameTYRP1_HUMAN
FullName5,6-dihydroxyindole-2-carboxylic acid oxidase
TaxID9606
Evidenceevidence at protein level
Length537
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesTYRP1

GO terms

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GOName
GO:0004503 monophenol monooxygenase activity
GO:0005737 cytoplasm
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0030318 melanocyte differentiation
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0032438 melanosome organization
GO:0033162 melanosome membrane
GO:0042438 melanin biosynthetic process
GO:0042470 melanosome
GO:0042803 protein homodimerization activity
GO:0043438 acetoacetic acid metabolic process
GO:0046872 metal ion binding
GO:0048023 positive regulation of melanin biosynthetic process
GO:0097708 intracellular vesicle

Subcellular Location

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Subcellular Location
Melanosome
Melanosome membrane

Domains

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DomainNameCategoryType
IPR002227 Tyrosinase copper-binding domainDomainDomain
IPR008922 Uncharacterised domain, di-copper centreFamilyHomologous superfamily

Diseases

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