Entity Details

Primary name SORCN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30626
EntryNameSORCN_HUMAN
FullNameSorcin
TaxID9606
Evidenceevidence at protein level
Length198
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesSRI

GO terms

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GOName
GO:0001508 action potential
GO:0002020 protease binding
GO:0005102 signaling receptor binding
GO:0005246 calcium channel regulator activity
GO:0005509 calcium ion binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005789 endoplasmic reticulum membrane
GO:0005790 smooth endoplasmic reticulum
GO:0005829 cytosol
GO:0006816 calcium ion transport
GO:0006880 intracellular sequestering of iron ion
GO:0006942 regulation of striated muscle contraction
GO:0007165 signal transduction
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0008016 regulation of heart contraction
GO:0010459 negative regulation of heart rate
GO:0010649 regulation of cell communication by electrical coupling
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016020 membrane
GO:0016529 sarcoplasmic reticulum
GO:0030018 Z disc
GO:0030315 T-tubule
GO:0033017 sarcoplasmic reticulum membrane
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042802 identical protein binding
GO:0042994 cytoplasmic sequestering of transcription factor
GO:0043679 axon terminus
GO:0044325 transmembrane transporter binding
GO:0044326 dendritic spine neck
GO:0046982 protein heterodimerization activity
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051924 regulation of calcium ion transport
GO:0055118 negative regulation of cardiac muscle contraction
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0070062 extracellular exosome
GO:0086004 regulation of cardiac muscle cell contraction
GO:1901077 regulation of relaxation of muscle
GO:1901841 regulation of high voltage-gated calcium channel activity
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction
GO:2000678 negative regulation of transcription regulatory region DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Sarcoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB11093 Calcium citrateDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule