Entity Details

Primary name L1CAM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP32004
EntryNameL1CAM_HUMAN
FullNameNeural cell adhesion molecule L1
TaxID9606
Evidenceevidence at protein level
Length1257
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesL1CAM

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006935 chemotaxis
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007160 cell-matrix adhesion
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0008046 axon guidance receptor activity
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0019904 protein domain specific binding
GO:0030424 axon
GO:0030425 dendrite
GO:0031175 neuron projection development
GO:0043025 neuronal cell body
GO:0044295 axonal growth cone
GO:0045773 positive regulation of axon extension
GO:0050808 synapse organization
GO:0050900 leukocyte migration
GO:0061564 axon development
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR026966 Neurofascin/L1/NrCAM, C-terminal domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00898 EthanolDrugbanksmall molecule

Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
L1CAM_HUMANPEA15_HUMANBioGRID, HPRD, IntAct16169070 details
L1CAM_HUMANEZRI_HUMANBioGRID, HPRD12070130 22846990 details
L1CAM_HUMANNCAN_HUMANBioGRID, HPRD10934197 7513709 details
L1CAM_HUMANITA5_HUMANBioGRID, HPRD10871287 details
L1CAM_HUMANITAV_HUMANBioGRID, HPRD10871287 details
L1CAM_HUMANCNTN2_HUMANBioGRID, HPRD12139915 details
L1CAM_HUMANNRP1_HUMANBioGRID16377081 25315821 details
L1CAM_HUMANRANB9_HUMANBioGRID, HPRD16000162 details
L1CAM_HUMANFGFR1_HUMANBioGRID18222703 23212305 details
L1CAM_HUMANL1CAM_HUMANBioGRID25315821 details
L1CAM_HUMANNRP2_HUMANBioGRID25315821 details
L1CAM_HUMANPLXA1_HUMANBioGRID25315821 details
L1CAM_HUMANPLXB1_HUMANBioGRID25315821 details
L1CAM_HUMANPRIO_HUMANBioGRID, HPRD, UniProt15146195 29791485 details
L1CAM_HUMANAP2A1_HUMANBioGRID12942088 details
L1CAM_HUMANNUMB_HUMANBioGRID, HPRD12942088 details
L1CAM_HUMANCALX_HUMANBioGRID22222883 details
L1CAM_HUMANRABX5_HUMANBioGRID23048039 details
L1CAM_HUMANEGFR_HUMANBioGRID22815787 details
L1CAM_HUMANERBB2_HUMANBioGRID22815787 details
L1CAM_HUMANERBB3_HUMANBioGRID22815787 details
L1CAM_HUMANRADI_HUMANHPRD12070130 details
L1CAM_HUMANANK1_HUMANHPRD11222639 details
L1CAM_HUMANMOES_HUMANHPRD12070130 details
L1CAM_HUMANKS6A1_HUMANHPRD8663493 details
L1CAM_HUMANCNTN1_HUMANHPRD7595520 details
L1CAM_HUMANKS6A2_HUMANHPRD8663493 details
L1CAM_HUMANCSK21_HUMANHPRD8592152 details
L1CAM_HUMANNCAM1_HUMANHPRD10611478 8509458 details
L1CAM_HUMANANK2_HUMANHPRD9832558 details