Entity Details

Primary name MTREX_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP42285
EntryNameMTREX_HUMAN
FullNameExosome RNA helicase MTR4
TaxID9606
Evidenceevidence at protein level
Length1042
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesMTREX

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0000460 maturation of 5.8S rRNA
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0006401 RNA catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0016076 snRNA catabolic process
GO:0016607 nuclear speck
GO:0031499 TRAMP complex
GO:0071013 catalytic step 2 spliceosome

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR012961 ATP-dependent RNA helicase Ski2, C-terminalDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR016438 ATP-dependent RNA helicase Ski2-likeFamilyFamily
IPR025696 rRNA-processing arch domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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