Entity Details

Primary name CXCR3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49682
EntryNameCXCR3_HUMAN
FullNameC-X-C chemokine receptor type 3
TaxID9606
Evidenceevidence at protein level
Length368
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesCXCR3

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001937 negative regulation of endothelial cell proliferation
GO:0002685 regulation of leukocyte migration
GO:0004950 chemokine receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0010818 T cell chemotaxis
GO:0016493 C-C chemokine receptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0016525 negative regulation of angiogenesis
GO:0019722 calcium-mediated signaling
GO:0019956 chemokine binding
GO:0019957 C-C chemokine binding
GO:0019958 C-X-C chemokine binding
GO:0030155 regulation of cell adhesion
GO:0038023 signaling receptor activity
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050921 positive regulation of chemotaxis
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0060326 cell chemotaxis
GO:0071954 chemokine (C-C motif) ligand 11 production
GO:1900118 negative regulation of execution phase of apoptosis
GO:1900119 positive regulation of execution phase of apoptosis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000355 Chemokine receptor familyFamilyFamily
IPR004070 CXC chemokine receptor 3FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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