Entity Details

Primary name HIRA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP54198
EntryNameHIRA_HUMAN
FullNameProtein HIRA
TaxID9606
Evidenceevidence at protein level
Length1017
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesHIRA

GO terms

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GOName
GO:0000417 HIR complex
GO:0000785 chromatin
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006336 DNA replication-independent nucleosome assembly
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009653 anatomical structure morphogenesis
GO:0016605 PML body
GO:0032991 protein-containing complex
GO:0042393 histone binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR011494 TUP1-like enhancer of splitDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR031120 WD repeat HIR1FamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
HIRA_HUMANRENT1_HUMANBioGRID, HPRD, IntAct15231747 details
HIRA_HUMANH33_HUMANBioGRID, HPRD, IntAct14718166 19410545 20211137 21047901 22195966 24209620 9731536 details
HIRA_HUMANASF1A_HUMANBioGRID, DIP, HPRD, IntAct, MINT15621527 16980972 17242207 18378699 19029251 21414300 21807893 23602572 24981860 26496610 27217568 28514442 34079125 details
HIRA_HUMANUBN1_HUMANBioGRID, IntAct19029251 21807893 22195966 22401310 23602572 24981860 27217568 details
HIRA_HUMANASF1B_HUMANBioGRID, DIP, IntAct, MINT16980972 24981860 26527279 28514442 details
HIRA_HUMANNFU1_HUMANBioGRID, HPRD11342215 details
HIRA_HUMANHIRP3_HUMANBioGRID, HPRD9710638 details
HIRA_HUMANH2B1K_HUMANBioGRID9710638 details
HIRA_HUMANH2B1D_HUMANBioGRID, HPRD9710638 details
HIRA_HUMANH2B1C_HUMANBioGRID9710638 details
HIRA_HUMANHNRPD_HUMANBioGRID15231747 details
HIRA_HUMANUBC9_HUMANBioGRID15561718 details
HIRA_HUMANOGT1_HUMANBioGRID27217568 details
HIRA_HUMANTRI55_HUMANBioGRID31391242 details
HIRA_HUMANTRI63_HUMANBioGRID31391242 details
HIRA_HUMANPAX7_HUMANHPRD9731536 details
HIRA_HUMANH2B2E_HUMANHPRD9710638 details
HIRA_HUMANMYC_HUMANBioGRID, IntAct21150319 23602572 29467282 details
HIRA_HUMANUBN2_HUMANBioGRID, IntAct19029251 24981860 details
HIRA_HUMANMEF2D_HUMANBioGRID21414300 details
HIRA_HUMANCABIN_HUMANBioGRID21414300 21807893 22195966 24981860 27217568 details
HIRA_HUMANDNJA2_HUMANBioGRID17242198 details
HIRA_HUMANRPB1_HUMANBioGRID22195966 23602572 details
HIRA_HUMANH4_HUMANBioGRID21724829 30804502 details
HIRA_HUMANH32_HUMANBioGRID21724829 details
HIRA_HUMANPML_HUMANBioGRID23222847 details
HIRA_HUMANDCD_HUMANBioGRID27217568 details
HIRA_HUMANHSP7C_HUMANBioGRID27217568 details
HIRA_HUMANRUVB1_HUMANBioGRID27217568 details
HIRA_HUMANBAG5_HUMANBioGRID27217568 details
HIRA_HUMANDSG1_HUMANBioGRID27217568 details
HIRA_HUMANLEG7_HUMANBioGRID27217568 details
HIRA_HUMANTIFA_HUMANBioGRID27217568 details
HIRA_HUMANSAMH1_HUMANBioGRID27217568 details
HIRA_HUMANM3K7_HUMANBioGRID27217568 details
HIRA_HUMANF263_HUMANBioGRID27217568 details
HIRA_HUMANSNF5_HUMANBioGRID23602572 details
HIRA_HUMANSMCA4_HUMANBioGRID23602572 details
HIRA_HUMANJUN_HUMANBioGRID23602572 details
HIRA_HUMANCTCF_HUMANBioGRID23602572 details
HIRA_HUMANGTF2I_HUMANBioGRID23602572 details
HIRA_HUMANSMCA2_HUMANBioGRID23602572 details
HIRA_HUMANOAS1_HUMANBioGRID28981850 details
HIRA_HUMANIFM1_HUMANBioGRID28981850 details
HIRA_HUMANCCNA2_HUMANHPRD11238922 details
HIRA_HUMANCDK2_HUMANHPRD11238922 details