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Entity Details
Primary name
PSA_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P55786
EntryName
PSA_HUMAN
FullName
Puromycin-sensitive aminopeptidase
TaxID
9606
Evidence
evidence at protein level
Length
919
SequenceStatus
complete
DateCreated
1997-11-01
DateModified
2021-06-02
Ontological Relatives
Genes
NPEPPS
GO terms
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GO
Name
GO:0000209
protein polyubiquitination
GO:0004177
aminopeptidase activity
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0006508
proteolysis
GO:0008270
zinc ion binding
GO:0042277
peptide binding
GO:0043171
peptide catabolic process
GO:0070006
metalloaminopeptidase activity
GO:0070062
extracellular exosome
GO:0071456
cellular response to hypoxia
GO:1903955
positive regulation of protein targeting to mitochondrion
Subcellular Location
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Subcellular Location
Cytoplasm
Nucleus
Domains
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Domain
Name
Category
Type
IPR001930
Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Family
Family
IPR014782
Peptidase M1, membrane alanine aminopeptidase
Domain
Domain
IPR024571
ERAP1-like C-terminal domain
Domain
Domain
IPR034016
Aminopeptidase N-type
Family
Family
IPR042097
Aminopeptidase N-like , N-terminal
Family
Homologous superfamily
Diseases
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Drugs
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Drug
Name
Source
Type
DB11638
Artenimol
Drugbank
small molecule
DB11781
Tosedostat
Drugbank
small molecule
Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
PSA_HUMAN
TAU_HUMAN
BioGRID
17154549
details
PSA_HUMAN
CRCM_HUMAN
IntAct
17353931
details
PSA_HUMAN
ARF6_HUMAN
IntAct
17353931
details
PSA_HUMAN
TIMP2_HUMAN
IntAct
17353931
details
PSA_HUMAN
TRAF6_HUMAN
IntAct
17353931
details
PSA_HUMAN
SOMA_HUMAN
IntAct
17353931
details
PSA_HUMAN
HLAB_HUMAN
IntAct
17353931
details
PSA_HUMAN
AAKB1_HUMAN
IntAct
17353931
details
PSA_HUMAN
HDAC5_HUMAN
BioGRID
21081666
details
PSA_HUMAN
CMKMT_HUMAN
BioGRID
23349634
details
PSA_HUMAN
F204A_HUMAN
BioGRID
26472760
details
PSA_HUMAN
CDK20_HUMAN
BioGRID
28534518
details
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