Entity Details

Primary name DHB7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56937
EntryNameDHB7_HUMAN
FullName3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
TaxID9606
Evidenceevidence at protein level
Length341
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesHSD17B7

GO terms

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GOName
GO:0000253 3-keto sterol reductase activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006695 cholesterol biosynthetic process
GO:0006703 estrogen biosynthetic process
GO:0008209 androgen metabolic process
GO:0016021 integral component of membrane
GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR042829 3-keto-steroid reductaseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule

Interactions

6 interactions