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Entity Details
Primary name
AP1S1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P61966
EntryName
AP1S1_HUMAN
FullName
AP-1 complex subunit sigma-1A
TaxID
9606
Evidence
evidence at protein level
Length
158
SequenceStatus
complete
DateCreated
2004-06-07
DateModified
2021-06-02
Ontological Relatives
Genes
AP1S1
GO terms
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GO
Name
GO:0000139
Golgi membrane
GO:0005765
lysosomal membrane
GO:0005794
Golgi apparatus
GO:0005829
cytosol
GO:0005905
clathrin-coated pit
GO:0006886
intracellular protein transport
GO:0006892
post-Golgi vesicle-mediated transport
GO:0006898
receptor-mediated endocytosis
GO:0009615
response to virus
GO:0016020
membrane
GO:0016192
vesicle-mediated transport
GO:0019886
antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030121
AP-1 adaptor complex
GO:0030659
cytoplasmic vesicle membrane
GO:0032588
trans-Golgi network membrane
GO:0043231
intracellular membrane-bounded organelle
GO:0050690
regulation of defense response to virus by virus
Subcellular Location
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Subcellular Location
Cytoplasmic vesicle membrane
Golgi apparatus
Membrane
Domains
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Domain
Name
Category
Type
IPR000804
Clathrin adaptor complex, small chain
Site
Conserved site
IPR011012
Longin-like domain superfamily
Family
Homologous superfamily
IPR016635
Adaptor protein complex, sigma subunit
Family
Family
IPR022775
AP complex, mu/sigma subunit
Domain
Domain
Diseases
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Drugs
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Interactions
12 interactions
Interactor
Partner
Sources
Publications
Link
AP1S1_HUMAN
AP1G1_HUMAN
BioGRID, HPRD
10535737
10747088
15758025
22939629
26344197
7593184
9733768
details
AP1S1_HUMAN
PECA1_HUMAN
IntAct
32814053
details
AP1S1_HUMAN
AP1S1_HUMAN
HPRD
9733768
details
AP1S1_HUMAN
PICK1_HUMAN
BioGRID, IntAct
32296183
details
AP1S1_HUMAN
RHOU_HUMAN
BioGRID
26598620
details
AP1S1_HUMAN
TGFR2_HUMAN
IntAct
32814053
details
AP1S1_HUMAN
AP2A2_HUMAN
HPRD
11707398
details
AP1S1_HUMAN
AP1G2_HUMAN
BioGRID
9733768
details
AP1S1_HUMAN
AP1M2_HUMAN
BioGRID, HPRD, IntAct
10535737
26186194
28514442
details
AP1S1_HUMAN
AP1S2_HUMAN
IntAct
17353931
details
AP1S1_HUMAN
EGFR_HUMAN
BioGRID
23956138
24797263
details
AP1S1_HUMAN
IKKE_HUMAN
IntAct
17353931
details
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