Entity Details

Primary name RHOB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP62745
EntryNameRHOB_HUMAN
FullNameRho-related GTP-binding protein RhoB
TaxID9606
Evidenceevidence at protein level
Length196
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesRHOB

GO terms

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GOName
GO:0000281 mitotic cytokinesis
GO:0001525 angiogenesis
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0006886 intracellular protein transport
GO:0006915 apoptotic process
GO:0007015 actin filament organization
GO:0007155 cell adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007266 Rho protein signal transduction
GO:0008333 endosome to lysosome transport
GO:0008360 regulation of cell shape
GO:0010008 endosome membrane
GO:0010595 positive regulation of endothelial cell migration
GO:0016477 cell migration
GO:0019003 GDP binding
GO:0019901 protein kinase binding
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0030336 negative regulation of cell migration
GO:0030865 cortical cytoskeleton organization
GO:0031410 cytoplasmic vesicle
GO:0031902 late endosome membrane
GO:0032154 cleavage furrow
GO:0032956 regulation of actin cytoskeleton organization
GO:0042995 cell projection
GO:0043065 positive regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0045766 positive regulation of angiogenesis
GO:0045786 negative regulation of cell cycle
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0061154 endothelial tube morphogenesis
GO:0070062 extracellular exosome
GO:0070301 cellular response to hydrogen peroxide
GO:0071479 cellular response to ionizing radiation

Subcellular Location

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Subcellular Location
Cell membrane
Cleavage furrow
Late endosome membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001806 Small GTPaseFamilyFamily
IPR003578 Small GTPase RhoFamilyFamily
IPR005225 Small GTP-binding protein domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00083 Botulinum toxin type ADrugbankbiotech

Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
RHOB_HUMANMAP1A_HUMANBioGRID, IntAct18056259 19637314 details
RHOB_HUMANBACD2_HUMANBioGRID, IntAct19637314 details
RHOB_HUMANSMUF1_HUMANBioGRID, IntAct25249323 30587574 details
RHOB_HUMANGDIR3_HUMANBioGRID, HPRD8939998 details
RHOB_HUMANNED4L_HUMANBioGRID26949039 details
RHOB_HUMANRHPN2_HUMANBioGRID, HPRD12473120 details
RHOB_HUMANARHG3_HUMANBioGRID, HPRD12221096 details
RHOB_HUMANBACD3_HUMANIntAct19637314 details
RHOB_HUMANSRTD1_HUMANIntAct19637314 details
RHOB_HUMANCTRO_HUMANBioGRID34079125 8543060 details
RHOB_HUMANNQO2_HUMANIntAct19637314 details
RHOB_HUMANFBX42_HUMANIntAct19637314 details
RHOB_HUMANNEK2_HUMANIntAct19637314 details
RHOB_HUMANPPIG_HUMANIntAct19637314 details
RHOB_HUMANDIAP1_HUMANBioGRID, mbinfo18218625 34079125 details
RHOB_HUMANFBN1_HUMANIntAct19637314 details
RHOB_HUMANNGEF_HUMANIntAct19637314 details
RHOB_HUMANDUT_HUMANIntAct19637314 details
RHOB_HUMANPDE6D_HUMANBioGRID, HPRD11786539 details
RHOB_HUMANNDKB_HUMANIntAct19637314 details
RHOB_HUMANDAAM1_HUMANmbinfo18218625 details
RHOB_HUMANEIF1B_HUMANIntAct19637314 details
RHOB_HUMANPRAF2_HUMANIntAct19637314 details
RHOB_HUMANGDIR1_HUMANBioGRID, IntAct19637314 34079125 details
RHOB_HUMANARHG1_HUMANBioGRID, IntAct19637314 34079125 details
RHOB_HUMANSERA_HUMANIntAct19637314 details
RHOB_HUMANRAC1_HUMANBioGRID25301945 details
RHOB_HUMANRBX1_HUMANBioGRID25540389 details
RHOB_HUMANPTN1_HUMANMINT14722096 details
RHOB_HUMANPGTB1_HUMANHPRD1400319 15451670 7713879 details
RHOB_HUMANFNTA_HUMANHPRD1400319 7713879 details
RHOB_HUMANCUL2_HUMANBioGRID25540389 details
RHOB_HUMANPP2AA_HUMANHPRD17163575 details
RHOB_HUMANINSR_HUMANBioGRID, MINT14722096 34079125 details