Entity Details

Primary name DEMA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08495
EntryNameDEMA_HUMAN
FullNameDematin
TaxID9606
Evidenceevidence at protein level
Length405
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesDMTN

GO terms

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GOName
GO:0003779 actin binding
GO:0005102 signaling receptor binding
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
GO:0010591 regulation of lamellipodium assembly
GO:0010763 positive regulation of fibroblast migration
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0010812 negative regulation of cell-substrate adhesion
GO:0012505 endomembrane system
GO:0014069 postsynaptic density
GO:0014731 spectrin-associated cytoskeleton
GO:0015629 actin cytoskeleton
GO:0030032 lamellipodium assembly
GO:0030036 actin cytoskeleton organization
GO:0030194 positive regulation of blood coagulation
GO:0030507 spectrin binding
GO:0030863 cortical cytoskeleton
GO:0031095 platelet dense tubular network membrane
GO:0031253 cell projection membrane
GO:0031410 cytoplasmic vesicle
GO:0032956 regulation of actin cytoskeleton organization
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0035585 calcium-mediated signaling using extracellular calcium source
GO:0043621 protein self-association
GO:0048471 perinuclear region of cytoplasm
GO:0048821 erythrocyte development
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0051015 actin filament binding
GO:0051017 actin filament bundle assembly
GO:0051489 regulation of filopodium assembly
GO:0051693 actin filament capping
GO:0051895 negative regulation of focal adhesion assembly
GO:0055085 transmembrane transport
GO:0065003 protein-containing complex assembly
GO:0070560 protein secretion by platelet
GO:0071277 cellular response to calcium ion
GO:0071320 cellular response to cAMP
GO:0090303 positive regulation of wound healing
GO:0090315 negative regulation of protein targeting to membrane
GO:0090527 actin filament reorganization
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901731 positive regulation of platelet aggregation
GO:2001046 positive regulation of integrin-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Endomembrane system
Membrane

Domains

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DomainNameCategoryType
IPR003128 Villin headpieceDomainDomain
IPR032402 Putative adherens-junction anchoring domainDomainDomain
IPR036886 Villin headpiece domain superfamilyFamilyHomologous superfamily

Diseases

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