Entity Details

Primary name CREB1
Entity type gene
Source Source Link

Details

PrimaryID1385
RefseqGeneNG_023299
SymbolCREB1
NamecAMP responsive element binding protein 1
Chromosome2
Location2q33.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-08-18
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCREB1_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005759 mitochondrial matrix
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007409 axonogenesis
GO:0007568 aging
GO:0007595 lactation
GO:0007613 memory
GO:0007623 circadian rhythm
GO:0008361 regulation of cell size
GO:0008542 visual learning
GO:0010033 response to organic substance
GO:0010629 negative regulation of gene expression
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0014823 response to activity
GO:0016032 viral process
GO:0019899 enzyme binding
GO:0021983 pituitary gland development
GO:0030424 axon
GO:0030544 Hsp70 protein binding
GO:0032916 positive regulation of transforming growth factor beta3 production
GO:0033363 secretory granule organization
GO:0033762 response to glucagon
GO:0034670 chemotaxis to arachidonic acid
GO:0035035 histone acetyltransferase binding
GO:0035094 response to nicotine
GO:0035497 cAMP response element binding
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0040018 positive regulation of multicellular organism growth
GO:0042493 response to drug
GO:0042752 regulation of circadian rhythm
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0045600 positive regulation of fat cell differentiation
GO:0045672 positive regulation of osteoclast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046887 positive regulation of hormone secretion
GO:0046889 positive regulation of lipid biosynthetic process
GO:0048145 regulation of fibroblast proliferation
GO:0050821 protein stabilization
GO:0055025 positive regulation of cardiac muscle tissue development
GO:0060251 regulation of glial cell proliferation
GO:0060430 lung saccule development
GO:0060509 type I pneumocyte differentiation
GO:0071294 cellular response to zinc ion
GO:0071300 cellular response to retinoic acid
GO:0071398 cellular response to fatty acid
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1901215 negative regulation of neuron death
GO:1902065 response to L-glutamate
GO:1990090 cellular response to nerve growth factor stimulus
GO:1990314 cellular response to insulin-like growth factor stimulus
GO:1990589 ATF4-CREB1 transcription factor complex
GO:1990763 arrestin family protein binding
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

179 interactions

InteractorPartnerSourcesPublicationsLink
CREB1BRCA1MINT9926942 details
CREB1SGK1HPRD, MINT15733869 details
CREB1CHD3BioGRID, HPRD, IntAct16169070 details
CREB1VIMBioGRID, HPRD, IntAct16169070 details
CREB1ERG28BioGRID, HPRD, IntAct16169070 details
CREB1RECQL5BioGRID, HPRD, IntAct16169070 details
CREB1RAB1ABioGRID, HPRD, IntAct16169070 details
CREB1HPS6HPRD, IntAct16169070 details
CREB1RPS6KA1BioGRID, HPRD, IntAct11175347 12235136 16282323 21832046 8688081 9687510 9829964 details
CREB1ATRBioGRID, IntAct16293623 details
CREB1TSSK4BioGRID, HPRD, IntAct15964553 21988832 details
CREB1EP300BioGRID, MINT10506141 11313407 12665587 17476304 21212407 21268077 22787115 26944191 7870179 details
CREB1CREBBPBioGRID, DIP, HPRD, IntAct, MINT10848610 10866654 11259575 11313407 11564156 12196545 12198160 12933667 15073328 15585582 15691881 16799563 17476304 17707401 18599546 20403362 20541704 23671189 27789289 7870179 8028671 8413673 8663317 9413984 9786917 9829964 details
CREB1ATF6BioGRID, IntAct20936779 details
CREB1TOX4BioGRID, IntAct20936779 details
CREB1CHD8BioGRID, IntAct20936779 details
CREB1HIPK3BioGRID, IntAct20936779 details
CREB1GTF2A1BioGRID, IntAct20936779 details
CREB1CRTC1BioGRID, IntAct20936779 32296183 details
CREB1POGZBioGRID, IntAct20936779 details
CREB1RNF111BioGRID, IntAct20936779 details
CREB1SREBF2BioGRID, IntAct20936779 details
CREB1PIAS1BioGRID, IntAct20936779 details
CREB1ZMYM2BioGRID, IntAct20936779 details
CREB1ZHX1BioGRID, IntAct20936779 details
CREB1UBE2IBioGRID, IntAct20936779 details
CREB1KIAA2026BioGRID, IntAct20936779 details
CREB1ZNF451BioGRID, IntAct20936779 details
CREB1PASKMINT21418524 details
CREB1TP53BioGRID, IntAct10848610 16611888 21295542 25241761 details
CREB1ATF1BioGRID, HPIDb, HPRD, MINT1655749 20102225 25609649 8384217 details
CREB1NFIL3BioGRID, HPIDb, IntAct, MINT20102225 25609649 28514442 details
CREB1CREB1BioGRID, HPIDb, MINT, UniProt20102225 23661758 25609649 details
CREB1BACH1HPIDb20102225 details
CREB1CREB3L3HPIDb20102225 details
CREB1SMCO1BioGRID, IntAct27107012 details
CREB1PIAS2BioGRID, IntAct32296183 details
CREB1AGR2BioGRID, IntAct32296183 details
CREB1CRTC2BioGRID, IntAct32296183 details
CREB1RNF4BioGRID, IntAct32296183 details
CREB1HTTBioGRID, IntAct16207717 32814053 details
CREB1TRIM22BioGRID, IntAct20211142 details
CREB1ZNF92BioGRID, IntAct20211142 details
CREB1MTF2BioGRID, IntAct20211142 details
CREB1SUZ12BioGRID, IntAct20211142 details
CREB1RFX3BioGRID, IntAct20211142 details
CREB1ZNF35BioGRID, IntAct20211142 details
CREB1ZNF436BioGRID, IntAct20211142 details
CREB1ABL1BioGRID, HPRD7565761 details
CREB1CEBPBBioGRID, HPRD12773552 details
CREB1KAT5BioGRID, HPRD10720489 details
CREB1CAMK2ABioGRID8663317 details
CREB1RBBP4BioGRID10866654 details
CREB1RPS6KA5BioGRID, HPRD11018520 11500364 11909979 16223362 9687510 9873047 details
CREB1RPS6KA4BioGRID, HPRD11175347 8688081 9687510 9792677 9829964 details
CREB1GLI2BioGRID, HPRD10074179 details
CREB1FHL5BioGRID, HPRD11046156 details
CREB1FHL2BioGRID11046156 details
CREB1FHL3BioGRID11046156 details
CREB1PRKACABioGRID11500364 12805224 details
CREB1HNF1BBioGRID9671480 details
CREB1NR3C1BioGRID, HPRD20203101 7621901 8449898 details
CREB1ATF7IPBioGRID20936779 details
CREB1HDAC1BioGRID12567184 20473547 details
CREB1POU2F1BioGRID12391146 details
CREB1CCDC6BioGRID20498639 details
CREB1PPP1CABioGRID20498639 details
CREB1RGS13BioGRID20974683 details
CREB1YY1BioGRID7769693 details
CREB1GSK3BBioGRID, HPRD12162494 14635195 details
CREB1GSK3ABioGRID14635195 details
CREB1SRA1BioGRID20398657 details
CREB1AKT1BioGRID, HPRD9829964 details
CREB1DAXXBioGRID22185778 details
CREB1PRKG1BioGRID, HPRD11175347 8688081 9687510 9829964 details
CREB1NR5A2BioGRID18191017 details
CREB1ATMBioGRID, HPRD15073328 16293623 details
CREB1DNMT3LBioGRID24952347 details
CREB1THRABioGRID, HPRD12805224 details
CREB1HIVEP1BioGRID32296183 details
CREB1PTENBioGRID31217297 details
CREB1MEIS1BioGRID, IntAct20159610 20541704 details
CREB1NFATC1BioGRID, MINT25609649 27637333 details
CREB1NFATC2BioGRID, MINT25609649 27637333 details
CREB1CREMBioGRID, HPRD, MINT22531917 25609649 7809053 details
CREB1JUNBioGRID, MINT2138276 25609649 details
CREB1KCNIP3BioGRID, HPRD12198160 details
CREB1H3C2BioGRID19279000 details
CREB1HDAC8BioGRID19070599 details
CREB1DACH1BioGRID16980615 details
CREB1SMARCA4BioGRID16675956 23671189 details
CREB1SMARCA5BioGRID, HPRD16675956 details
CREB1CARM1BioGRID16330542 details
CREB1MYOD1BioGRID12665587 details
CREB1HDAC2BioGRID12567184 20473547 details
CREB1TAF4BioGRID15703171 details
CREB1DNMT3BBioGRID19786833 details
CREB1ATXN3BioGRID11572863 details
CREB1SIRT1BioGRID23382074 details
CREB1YAP1BioGRID23532963 31496812 32220262 details
CREB1MAPK14BioGRID, HPRD11377386 23532963 details
CREB1DEAF1BioGRID23846693 details
CREB1NCOR1BioGRID24315104 details
CREB1CTNNB1BioGRID17962194 19223551 23671189 details
CREB1TRAF3BioGRID26755589 details
CREB1H3C1BioGRID12933667 details
CREB1STAT3BioGRID26508788 details
CREB1RFX5BioGRID23671189 details
CREB1NFYBBioGRID23671189 details
CREB1HIF1ABioGRID27808477 details
CREB1DYRK1AHPRD15694837 details
CREB1SRFHPRD7551568 9388250 details
CREB1GTF2F2HPRD8628277 details
CREB1RPS6KA3HPRD11160957 11175347 8688081 9687510 9829964 details
CREB1PDX1HPRD7505393 details
CREB1RPS6KA2HPRD11175347 11698596 8688081 9687510 9829964 details
CREB1EDF1HPRD10567391 details
CREB1MAPKAPK2HPRD8887554 details
CREB1SOX9HPRD19113914 details
CREB1ULK2IntAct20562859 details
CREB1NFIXBioGRID, MINT25609649 details
CREB1H2BC1BioGRID, MINT25609649 details
CREB1HOXD13BioGRID, MINT25609649 details
CREB1MECP2BioGRID, MINT25609649 details
CREB1HMGA2BioGRID, MINT25609649 details
CREB1H2BC11BioGRID, MINT25609649 details
CREB1NIT2BioGRID, MINT25609649 details
CREB1NFYABioGRID, MINT25609649 details
CREB1TTF2BioGRID, MINT25609649 details
CREB1XRCC1BioGRID, MINT25609649 details
CREB1POLR2ABioGRID, MINT25609649 details
CREB1JUNDBioGRID, MINT25609649 details
CREB1H3-4BioGRID, MINT25609649 details
CREB1RECQLBioGRID, MINT25609649 details
CREB1ZNF131BioGRID, MINT25609649 details
CREB1NFICBioGRID, MINT25609649 details
CREB1ZBTB21BioGRID, MINT25609649 details
CREB1ARNTBioGRID, MINT25609649 details
CREB1NFIABioGRID, MINT25609649 details
CREB1C5orf24BioGRID, MINT25609649 details
CREB1HMGA1BioGRID, MINT25609649 details
CREB1PBX2BioGRID, MINT25609649 details
CREB1FOXA1BioGRID, MINT25609649 details
CREB1FOXC1BioGRID, MINT25609649 details
CREB1FOXC2BioGRID, MINT25609649 details
CREB1FOXE1BioGRID, MINT25609649 details
CREB1PSME3IP1BioGRID, MINT25609649 details
CREB1ANKRD17BioGRID, MINT25609649 details
CREB1DNAAF8BioGRID, IntAct28514442 details
CREB1MIA2BioGRID, IntAct28514442 details
CREB1ARHGAP22BioGRID, IntAct28514442 details
CREB1CSGALNACT2BioGRID, IntAct28514442 details
CREB1FEZ1BioGRID, IntAct28514442 details
CREB1GPS2BioGRID, IntAct26186194 28514442 details
CREB1ORC6BioGRID, IntAct26186194 28514442 details
CREB1TRIM11BioGRID, IntAct28514442 details
CREB1PRR20AIntAct28514442 details
CREB1PRR20BIntAct28514442 details
CREB1PRR20CIntAct28514442 details
CREB1PRR20DIntAct28514442 details
CREB1PRR20EBioGRID, IntAct28514442 details
CREB1PFDN4BioGRID, IntAct28514442 details
CREB1ARIH1BioGRID, IntAct28514442 details
CREB1TUFT1BioGRID, IntAct26186194 28514442 details
CREB1TRIM5BioGRID, IntAct28514442 details
CREB1IFT74BioGRID, IntAct28514442 details
CREB1SYCP1BioGRID, IntAct28514442 details
CREB1TRPV5BioGRID, IntAct26186194 28514442 details
CREB1SEC22BBioGRID, IntAct30021884 details
CREB1ATF7BioGRID22939629 details
CREB1DR1BioGRID22939629 details
CREB1ARV1BioGRID26186194 details
CREB1LAX1BioGRID26186194 details
CREB1ATF2BioGRID26344197 details
CREB1ESR2BioGRID29509190 details
CREB1H4C1BioGRID30804502 details
CREB1CICBioGRID29844126 details
CREB1VEGFAIntAct26350463 details
CREB1MKRN2BioGRID32460013 details