Entity Details

Primary name PYDC2
Entity type gene
Source Source Link

Details

PrimaryID152138
RefseqGene
SymbolPYDC2
Namepyrin domain containing 2
Chromosome3
Location3q28
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPYDC2_HUMAN

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032691 negative regulation of interleukin-1 beta production
GO:0045087 innate immune response
GO:0050728 negative regulation of inflammatory response
GO:1900226 negative regulation of NLRP3 inflammasome complex assembly
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
PYDC2NLRP2HPRD, UniProt17178784 details
PYDC2PYCARDHPRD, UniProt17178784 17339483 details
PYDC2NLRP12UniProt17178784 details
PYDC2NLRP4UniProt17178784 details
PYDC2NLRP1UniProt17178784 details