Entity Details

Primary name FCL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13630
EntryNameFCL_HUMAN
FullNameGDP-L-fucose synthase
TaxID9606
Evidenceevidence at protein level
Length321
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesGFUS

GO terms

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GOName
GO:0005829 cytosol
GO:0007159 leukocyte cell-cell adhesion
GO:0009055 electron transfer activity
GO:0010595 positive regulation of endothelial cell migration
GO:0019673 GDP-mannose metabolic process
GO:0042351 'de novo' GDP-L-fucose biosynthetic process
GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity
GO:0042802 identical protein binding
GO:0047918 GDP-mannose 3,5-epimerase activity
GO:0050577 GDP-L-fucose synthase activity
GO:0070062 extracellular exosome
GO:1904906 positive regulation of endothelial cell-matrix adhesion via fibronectin

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001509 NAD-dependent epimerase/dehydrataseDomainDomain
IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthaseFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule

Interactions

6 interactions