Entity Details

Primary name DPOA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14181
EntryNameDPOA2_HUMAN
FullNameDNA polymerase alpha subunit B
TaxID9606
Evidenceevidence at protein level
Length598
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesPOLA2

GO terms

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GOName
GO:0003677 DNA binding
GO:0005654 nucleoplasm
GO:0005658 alpha DNA polymerase:primase complex
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of RNA primer
GO:0006270 DNA replication initiation
GO:0032201 telomere maintenance via semi-conservative replication

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR007185 DNA polymerase alpha/delta/epsilon, subunit BDomainDomain
IPR013627 DNA polymerase alpha, subunit B, N-terminalDomainDomain
IPR016722 DNA polymerase alpha, subunit BFamilyFamily
IPR043034 DNA polymerase alpha, subunit B, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00851 DacarbazineDrugbanksmall molecule

Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
DPOA2_HUMANDCP2_HUMANBioGRID, HPRD, IntAct15231747 details
DPOA2_HUMANASCC2_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANATPG_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANDDX24_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANEZH2_HUMANBioGRID, HPRD, IntAct16169070 27634302 details
DPOA2_HUMANAKTIP_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANKLF6_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANCBPE_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANCREL1_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANFGFR3_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANPR38A_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANAMRP_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANNH2L1_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANSETB1_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANF219A_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANDHX34_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANIBP3_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANSTK40_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANULK2_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANXPP1_HUMANBioGRID, HPRD, IntAct16169070 details
DPOA2_HUMANDPOLA_HUMANBioGRID, HPRD, IntAct12138179 22863883 22939629 26344197 8223465 details
DPOA2_HUMANPRI2_HUMANBioGRID, IntAct12138179 22863883 22939629 28757209 details
DPOA2_HUMANSFRP3_HUMANBioGRID, MINT21900206 details
DPOA2_HUMANHDAC6_HUMANBioGRID, MINT21900206 details
DPOA2_HUMANKCNE3_HUMANBioGRID, MINT21900206 details
DPOA2_HUMANNR4A1_HUMANBioGRID, MINT21900206 details
DPOA2_HUMANMFHA1_HUMANBioGRID, IntAct29513927 details
DPOA2_HUMANCASP6_HUMANIntAct32814053 details
DPOA2_HUMANERN1_HUMANIntAct32814053 details
DPOA2_HUMANHSP72_HUMANIntAct32814053 details
DPOA2_HUMANLAMP2_HUMANIntAct32814053 details
DPOA2_HUMANRAN_HUMANIntAct32814053 details
DPOA2_HUMANSYSC_HUMANIntAct32814053 details
DPOA2_HUMANSTIP1_HUMANIntAct32814053 details
DPOA2_HUMANSHLB1_HUMANIntAct32814053 details
DPOA2_HUMANPR40A_HUMANIntAct32814053 details
DPOA2_HUMANHGH1_HUMANBioGRID, HPRD16169070 details
DPOA2_HUMANRBM23_HUMANBioGRID, HPRD16169070 details
DPOA2_HUMANIF6_HUMANBioGRID, HPRD16169070 details
DPOA2_HUMANPARP1_HUMANBioGRID9518481 details
DPOA2_HUMANHELB_HUMANBioGRID, HPRD12181327 details
DPOA2_HUMANA4_HUMANBioGRID21832049 details
DPOA2_HUMANCENPR_HUMANIntAct16169070 details