Entity Details

Primary name GATA3
Entity type gene
Source Source Link

Details

PrimaryID2625
RefseqGeneNG_015859
SymbolGATA3
NameGATA binding protein 3
Chromosome10
Location10p14
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsGATA3_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001701 in utero embryonic development
GO:0001709 cell fate determination
GO:0001764 neuron migration
GO:0001806 type IV hypersensitivity
GO:0001817 regulation of cytokine production
GO:0001822 kidney development
GO:0001823 mesonephros development
GO:0002088 lens development in camera-type eye
GO:0002520 immune system development
GO:0002572 pro-T cell differentiation
GO:0003180 aortic valve morphogenesis
GO:0003215 cardiac right ventricle morphogenesis
GO:0003281 ventricular septum development
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005134 interleukin-2 receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006338 chromatin remodeling
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006952 defense response
GO:0006959 humoral immune response
GO:0007165 signal transduction
GO:0007411 axon guidance
GO:0007596 blood coagulation
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0008584 male gonad development
GO:0009615 response to virus
GO:0009653 anatomical structure morphogenesis
GO:0009791 post-embryonic development
GO:0009967 positive regulation of signal transduction
GO:0010332 response to gamma radiation
GO:0010595 positive regulation of endothelial cell migration
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010975 regulation of neuron projection development
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0016579 protein deubiquitination
GO:0019221 cytokine-mediated signaling pathway
GO:0030217 T cell differentiation
GO:0030218 erythrocyte differentiation
GO:0030856 regulation of epithelial cell differentiation
GO:0031929 TOR signaling
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0032736 positive regulation of interleukin-13 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032754 positive regulation of interleukin-5 production
GO:0033600 negative regulation of mammary gland epithelial cell proliferation
GO:0035162 embryonic hemopoiesis
GO:0035457 cellular response to interferon-alpha
GO:0035799 ureter maturation
GO:0035898 parathyroid hormone secretion
GO:0042421 norepinephrine biosynthetic process
GO:0042472 inner ear morphogenesis
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043523 regulation of neuron apoptotic process
GO:0043583 ear development
GO:0043627 response to estrogen
GO:0045061 thymic T cell selection
GO:0045064 T-helper 2 cell differentiation
GO:0045087 innate immune response
GO:0045165 cell fate commitment
GO:0045471 response to ethanol
GO:0045582 positive regulation of T cell differentiation
GO:0045599 negative regulation of fat cell differentiation
GO:0045786 negative regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048469 cell maturation
GO:0048485 sympathetic nervous system development
GO:0048538 thymus development
GO:0048568 embryonic organ development
GO:0048589 developmental growth
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0050728 negative regulation of inflammatory response
GO:0050852 T cell receptor signaling pathway
GO:0051569 regulation of histone H3-K4 methylation
GO:0051897 positive regulation of protein kinase B signaling
GO:0060017 parathyroid gland development
GO:0060037 pharyngeal system development
GO:0060065 uterus development
GO:0060231 mesenchymal to epithelial transition
GO:0060374 mast cell differentiation
GO:0060676 ureteric bud formation
GO:0061085 regulation of histone H3-K27 methylation
GO:0061290 canonical Wnt signaling pathway involved in metanephric kidney development
GO:0070888 E-box binding
GO:0071353 cellular response to interleukin-4
GO:0071356 cellular response to tumor necrosis factor
GO:0071442 positive regulation of histone H3-K14 acetylation
GO:0071599 otic vesicle development
GO:0071773 cellular response to BMP stimulus
GO:0071837 HMG box domain binding
GO:0072107 positive regulation of ureteric bud formation
GO:0072178 nephric duct morphogenesis
GO:0072179 nephric duct formation
GO:0072182 regulation of nephron tubule epithelial cell differentiation
GO:0072197 ureter morphogenesis
GO:0072676 lymphocyte migration
GO:0090102 cochlea development
GO:1901536 negative regulation of DNA demethylation
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000114 regulation of establishment of cell polarity
GO:2000146 negative regulation of cell motility
GO:2000352 negative regulation of endothelial cell apoptotic process
GO:2000553 positive regulation of T-helper 2 cell cytokine production
GO:2000607 negative regulation of cell proliferation involved in mesonephros development
GO:2000611 positive regulation of thyroid hormone generation
GO:2000617 positive regulation of histone H3-K9 acetylation
GO:2000679 positive regulation of transcription regulatory region DNA binding
GO:2000683 regulation of cellular response to X-ray
GO:2000703 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
GO:2000734 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

Diseases

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Interactions

87 interactions

InteractorPartnerSourcesPublicationsLink
GATA3PSMA3BioGRID, IntAct25416956 details
GATA3HDAC2BioGRID, IntAct26028330 29453984 31409898 details
GATA3HDAC1BioGRID, IntAct26028330 29453984 31409898 details
GATA3MTA3IntAct26028330 details
GATA3EHMT2IntAct26028330 details
GATA3KDM1ABioGRID, IntAct26028330 31409898 details
GATA3LCKBioGRID, IntAct26871637 details
GATA3CYSRT1BioGRID, IntAct32296183 details
GATA3KRTAP13-2BioGRID, IntAct32296183 details
GATA3PLEKHG4BioGRID, IntAct32296183 details
GATA3KRTAP6-2BioGRID, IntAct32296183 details
GATA3KRTAP12-1BioGRID, IntAct32296183 details
GATA3ACTN2BioGRID, IntAct25910212 details
GATA3HDAC3BioGRID, DIP17075044 29453984 details
GATA3TRIM55BioGRID, IntAct31391242 details
GATA3HIF1ABioGRID, MINT28263977 details
GATA3CHATIntAct32814053 details
GATA3FGFR3IntAct32814053 details
GATA3RARBBioGRID, IntAct20211142 details
GATA3LMO1BioGRID, HPRD9020185 9819382 details
GATA3SP1BioGRID18338249 details
GATA3REPIN1BioGRID18338249 details
GATA3SPI1BioGRID10364157 details
GATA3CDK2BioGRID24820417 details
GATA3FBXW7BioGRID24820417 details
GATA3MAPK14BioGRID24820417 details
GATA3CREBBPBioGRID29453984 details
GATA3TRIM63BioGRID31391242 details
GATA3ZFPM2HPRD14985365 details
GATA3TAL1BioGRID, HPRD, MINT21179004 9819382 details
GATA3SOX4InnateDB22751141 details
GATA3MDM2BioGRID, IntAct15975924 26028330 details
GATA3HDAC5BioGRID, DIP17075044 details
GATA3TBX21BioGRID, DIP17075044 details
GATA3GCM1IntAct26899996 details
GATA3LMO2BioGRID, HPRD9819382 details
GATA3BMI1BioGRID17114435 details
GATA3HDAC4BioGRID16922677 details
GATA3MYBBioGRID22039304 details
GATA3BRCA1BioGRID22120723 details
GATA3USP21BioGRID23395819 details
GATA3FOXP3BioGRID23395819 details
GATA3TCF7L2BioGRID22951069 details
GATA3RCOR1BioGRID31409898 details
GATA3SATB1HPRD17057718 details
GATA3ETS1HPRD10212281 details
GATA3ETS2HPRD10212281 details
GATA3MED1HPRD11724781 details
GATA3RARAIntAct25303530 details
GATA3STAT1IntAct25303530 details
GATA3FOXA1BioGRID, IntAct25303530 27926873 details
GATA3FOSIntAct25303530 details
GATA3TFAP2CIntAct25303530 details
GATA3ESR1BioGRID, IntAct23403292 25303530 26153859 details
GATA3RARGIntAct25303530 details
GATA3MBD3IntAct26028330 details
GATA3RBBP4IntAct26028330 details
GATA3VTNIntAct26028330 details
GATA3STK38IntAct26028330 details
GATA3SDAD1IntAct26028330 details
GATA3PRMT5IntAct26028330 details
GATA3HSP90AA1IntAct26028330 details
GATA3KIF11IntAct26028330 details
GATA3MMRN1IntAct26028330 details
GATA3SPAG9IntAct26028330 details
GATA3UBR3IntAct26028330 details
GATA3JMJD1CIntAct26028330 details
GATA3ZEB2IntAct26028330 details
GATA3C4AIntAct26153859 details
GATA3C4BIntAct26153859 details
GATA3RNF4BioGRID29180619 details
GATA3CICBioGRID29844126 details
GATA3TFF1IntAct25303530 details
GATA3GREB1IntAct25303530 details
GATA3FOXC1IntAct25303530 details
GATA3MYCIntAct25303530 26028330 details
GATA3VAPBIntAct26028330 details
GATA3AURKAIP1IntAct26028330 details
GATA3ACTR6IntAct26028330 details
GATA3ZNF217IntAct26028330 details
GATA3BCAS3IntAct26028330 details
GATA3NCOA3IntAct26028330 details
GATA3POLR1FIntAct26028330 details
GATA3KMT2EIntAct26028330 details
GATA3CDH2IntAct26028330 details
GATA3FN1IntAct26028330 details
GATA3CCL5IntAct10640782 details