Entity Details

Primary name KCNB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14721
EntryNameKCNB1_HUMAN
FullNamePotassium voltage-gated channel subfamily B member 1
TaxID9606
Evidenceevidence at protein level
Length858
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesKCNB1

GO terms

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GOName
GO:0001508 action potential
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005886 plasma membrane
GO:0006904 vesicle docking involved in exocytosis
GO:0007215 glutamate receptor signaling pathway
GO:0008076 voltage-gated potassium channel complex
GO:0010701 positive regulation of norepinephrine secretion
GO:0016021 integral component of membrane
GO:0016328 lateral plasma membrane
GO:0030424 axon
GO:0030425 dendrite
GO:0031669 cellular response to nutrient levels
GO:0032590 dendrite membrane
GO:0032809 neuronal cell body membrane
GO:0033605 positive regulation of catecholamine secretion
GO:0034765 regulation of ion transmembrane transport
GO:0042383 sarcolemma
GO:0042593 glucose homeostasis
GO:0043204 perikaryon
GO:0044325 transmembrane transporter binding
GO:0045211 postsynaptic membrane
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0046676 negative regulation of insulin secretion
GO:0046982 protein heterodimerization activity
GO:0050796 regulation of insulin secretion
GO:0051260 protein homooligomerization
GO:0071333 cellular response to glucose stimulus
GO:0071805 potassium ion transmembrane transport
GO:0072659 protein localization to plasma membrane
GO:0090314 positive regulation of protein targeting to membrane
GO:0098900 regulation of action potential
GO:1900454 positive regulation of long-term synaptic depression
GO:2000671 regulation of motor neuron apoptotic process

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Lateral cell membrane
Membrane
Perikaryon

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR003131 Potassium channel tetramerisation-type BTB domainDomainDomain
IPR003968 Potassium channel, voltage dependent, KvFamilyFamily
IPR003973 Potassium channel, voltage dependent, Kv2FamilyFamily
IPR004350 Potassium channel, voltage dependent, Kv2.1FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028325 Voltage-gated potassium channelFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB06637 DalfampridineDrugbanksmall molecule