Entity Details

Primary name HPN
Entity type gene
Source Source Link

Details

PrimaryID3249
RefseqGene
SymbolHPN
Namehepsin
Chromosome19
Location19q13.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHEPS_HUMAN

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006508 proteolysis
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0008360 regulation of cell shape
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010756 positive regulation of plasminogen activation
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030307 positive regulation of cell growth
GO:0034769 basement membrane disassembly
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043923 positive regulation by host of viral transcription
GO:0048012 hepatocyte growth factor receptor signaling pathway
GO:0050680 negative regulation of epithelial cell proliferation
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0070008 serine-type exopeptidase activity
GO:0070062 extracellular exosome
GO:0071805 potassium ion transmembrane transport
GO:0090103 cochlea morphogenesis
GO:0097066 response to thyroid hormone
GO:0097195 pilomotor reflex
GO:2000347 positive regulation of hepatocyte proliferation
GO:2000611 positive regulation of thyroid hormone generation

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
HPNBNIP3BioGRID, IntAct32296183 details
HPNSFTPCBioGRID, IntAct32296183 details
HPNUPK2BioGRID, IntAct32296183 details
HPNGLP1RBioGRID23864651 details
HPNEGFRBioGRID19911255 details
HPNHGFHPRD15792801 details
HPNF7HPRD7814421 details
HPNSP110BioGRID31753913 details
HPNHNRNPLBioGRID28611215 details