Entity Details

Primary name ITGAV
Entity type gene
Source Source Link

Details

PrimaryID3685
RefseqGene
SymbolITGAV
Nameintegrin subunit alpha V
Chromosome2
Location2q32.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-02-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsITAV_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001618 virus receptor activity
GO:0001846 opsonin binding
GO:0001968 fibronectin binding
GO:0002020 protease binding
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005080 protein kinase C binding
GO:0005178 integrin binding
GO:0005245 voltage-gated calcium channel activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007229 integrin-mediated signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010888 negative regulation of lipid storage
GO:0015026 coreceptor activity
GO:0016020 membrane
GO:0030198 extracellular matrix organization
GO:0030335 positive regulation of cell migration
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031528 microvillus membrane
GO:0031589 cell-substrate adhesion
GO:0032369 negative regulation of lipid transport
GO:0032587 ruffle membrane
GO:0033627 cell adhesion mediated by integrin
GO:0033690 positive regulation of osteoblast proliferation
GO:0034113 heterotypic cell-cell adhesion
GO:0034446 substrate adhesion-dependent cell spreading
GO:0034683 integrin alphav-beta3 complex
GO:0034684 integrin alphav-beta5 complex
GO:0034685 integrin alphav-beta6 complex
GO:0034686 integrin alphav-beta8 complex
GO:0035579 specific granule membrane
GO:0035866 alphav-beta3 integrin-PKCalpha complex
GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
GO:0035868 alphav-beta3 integrin-HMGB1 complex
GO:0035987 endodermal cell differentiation
GO:0038027 apolipoprotein A-I-mediated signaling pathway
GO:0043277 apoptotic cell clearance
GO:0043312 neutrophil degranulation
GO:0045335 phagocytic vesicle
GO:0045785 positive regulation of cell adhesion
GO:0046718 viral entry into host cell
GO:0046872 metal ion binding
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0050431 transforming growth factor beta binding
GO:0050748 negative regulation of lipoprotein metabolic process
GO:0050764 regulation of phagocytosis
GO:0050840 extracellular matrix binding
GO:0050900 leukocyte migration
GO:0050919 negative chemotaxis
GO:0070062 extracellular exosome
GO:0070371 ERK1 and ERK2 cascade
GO:0070588 calcium ion transmembrane transport
GO:0071604 transforming growth factor beta production
GO:0085017 entry into host cell by a symbiont-containing vacuole
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1901388 regulation of transforming growth factor beta activation
GO:1905598 negative regulation of low-density lipoprotein receptor activity
GO:1990430 extracellular matrix protein binding
GO:2000536 negative regulation of entry of bacterium into host cell
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Diseases

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Interactions

104 interactions

InteractorPartnerSourcesPublicationsLink
ITGAVITGB3BioGRID, DIP, HPRD, I2D, IntAct, MINT10891446 11546839 11884718 15299032 16099422 1694173 20639902 22178926 24658351 25792870 9686320 details
ITGAVANGPTL3HPRD, IntAct11877390 details
ITGAVITGB6DIP, HPRD1532572 21677751 25383667 8120056 details
ITGAVITGB1BioGRID, DIP16424009 22178926 25792870 26344197 details
ITGAVSERPINH1IntAct32814053 details
ITGAVPRKACAIntAct32814053 details
ITGAVRAD23AIntAct32814053 details
ITGAVTGFBR2IntAct32814053 details
ITGAVLRRK1IntAct32814053 details
ITGAVCCN3BioGRID12902636 details
ITGAVAUP1BioGRID12042322 details
ITGAVL1CAMBioGRID, HPRD10871287 details
ITGAVCCN1BioGRID, HPRD10821835 11287419 details
ITGAVPXNBioGRID16600665 30120307 details
ITGAVSPP1BioGRID, HPRD10835423 7592829 details
ITGAVLGALS3BPBioGRID24362527 details
ITGAVMAPK3BioGRID23640055 details
ITGAVPLA2G2ABioGRID18635536 details
ITGAVPAK4BioGRID, HPRD12356872 23254288 details
ITGAVUBCBioGRID28190767 details
ITGAVITGB5BioGRID, HPRD, IntAct12844492 1694173 7689573 details
ITGAVITGB8DIP, HPRD, IntAct1918072 30061598 details
ITGAVPTPRZ1BioGRID, I2D19141530 20639902 details
ITGAVPTK2BioGRID, IntAct12844492 19889638 23397142 details
ITGAVAGMATBioGRID, IntAct27173435 unassigned1312 details
ITGAVEDIL3BioGRID, HPRD, IntAct11959660 28514442 details
ITGAVTGFB1DIP, HPRD11970960 21677751 details
ITGAVADAM17UniProt30455686 details
ITGAVILKBioGRID8538749 details
ITGAVPLP1BioGRID, HPRD12196561 details
ITGAVMMP2BioGRID, HPRD11134507 22349830 23254288 details
ITGAVCSF1RBioGRID16600665 details
ITGAVCBLBioGRID16600665 details
ITGAVBCAR1BioGRID16600665 details
ITGAVPHKA2BioGRID16600665 details
ITGAVTHBS1BioGRID14963009 details
ITGAVEPHA2BioGRID23874206 details
ITGAVNCOR1BioGRID23640055 details
ITGAVNCOR2BioGRID23640055 details
ITGAVEP300BioGRID23640055 details
ITGAVMAPK1BioGRID23640055 details
ITGAVSTAT1BioGRID23640055 details
ITGAVSHC1BioGRID19889638 details
ITGAVADAM9BioGRID, HPRD15361064 16373656 details
ITGAVERBB2BioGRID26222911 details
ITGAVANGPT2BioGRID16424009 details
ITGAVNCLBioGRID23161541 details
ITGAVITGA4BioGRID25792870 details
ITGAVITGAVBioGRID25792870 details
ITGAVPTNBioGRID19141530 details
ITGAVMETBioGRID28973887 details
ITGAVCXCL12BioGRID23381805 details
ITGAVST7BioGRID29395067 details
ITGAVPDGFRAHPRD11953315 details
ITGAVF2RHPRD11278329 details
ITGAVAZGP1HPRD9813179 details
ITGAVP2RY2HPRD11331301 details
ITGAVCD47HPRD10545994 details
ITGAVCALRHPRD12196561 details
ITGAVICAM4HPRD11435317 details
ITGAVMMP14HPRD11741954 details
ITGAVTHY1HPRD15897908 details
ITGAVNID1HPRD9686320 details
ITGAVVTNIntAct1694173 details
ITGAVFN1BioGRID, DIP, IntAct1694173 19738201 24658351 details
ITGAVVWFIntAct1694173 details
ITGAVPLPP3MINT16099422 details
ITGAVFGGIntAct24789099 details
ITGAVSUSD4BioGRID, IntAct26186194 28514442 details
ITGAVST3GAL1BioGRID, IntAct28514442 details
ITGAVTAFAZZINBioGRID, IntAct26186194 28514442 details
ITGAVGGHBioGRID, IntAct28514442 details
ITGAVINSL5BioGRID, IntAct28514442 details
ITGAVDEFA1BioGRID, IntAct28514442 details
ITGAVDEFA1BIntAct28514442 details
ITGAVST8SIA4BioGRID, IntAct28514442 details
ITGAVTMEM25BioGRID, IntAct28514442 details
ITGAVLYZL2BioGRID, IntAct28514442 details
ITGAVPTCH1BioGRID, IntAct28514442 details
ITGAVTNFSF13BBioGRID, IntAct28514442 details
ITGAVDPEP2BioGRID, IntAct26186194 28514442 details
ITGAVNAAABioGRID, IntAct28514442 details
ITGAVTCTN2BioGRID, IntAct28514442 details
ITGAVB3GNT2BioGRID, IntAct28514442 details
ITGAVFUT8BioGRID, IntAct28514442 details
ITGAVTGFB3DIP25383667 details
ITGAVLAMP1BioGRID, IntAct29568061 details
ITGAVCD81IntAct32900848 details
ITGAVFBXO6BioGRID22268729 32409323 details
ITGAVMCATBioGRID22939629 details
ITGAVKRT3BioGRID22939629 details
ITGAVNTRK1BioGRID25921289 details
ITGAVPSMD12BioGRID26344197 details
ITGAVFCGR3BBioGRID28514442 details
ITGAVRNF4BioGRID29180619 details
ITGAVVIRMABioGRID29507755 details
ITGAVVDAC2BioGRID31536960 details
ITGAVVDAC1BioGRID31536960 details
ITGAVVDAC3BioGRID31536960 details
ITGAVOTULINLBioGRID31056421 details
ITGAVCUL9BioGRID31343991 details
ITGAVATP2A1BioGRID34079125 details
ITGAVCAV1BioGRID34079125 details
ITGAVTRIM25BioGRID29117863 details