Entity Details

Primary name PCH2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15645
EntryNamePCH2_HUMAN
FullNamePachytene checkpoint protein 2 homolog
TaxID9606
Evidenceevidence at protein level
Length432
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesTRIP13

GO terms

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GOName
GO:0001556 oocyte maturation
GO:0001673 male germ cell nucleus
GO:0003712 transcription coregulator activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005694 chromosome
GO:0006302 double-strand break repair
GO:0006366 transcription by RNA polymerase II
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0007130 synaptonemal complex assembly
GO:0007131 reciprocal meiotic recombination
GO:0007141 male meiosis I
GO:0007144 female meiosis I
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0048477 oogenesis
GO:0051598 meiotic recombination checkpoint signaling

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001270 ClpA/B familyFamilyFamily
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR003960 ATPase, AAA-type, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR044539 Pachytene checkpoint protein 2-likeFamilyFamily

Diseases

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Interactions

117 interactions

InteractorPartnerSourcesPublicationsLink
PCH2_HUMANDPYL1_HUMANBioGRID, HPRD, IntAct16169070 details
PCH2_HUMANPCH2_HUMANBioGRID, HPRD, IntAct11591653 16169070 16189514 25416956 26324890 32296183 details
PCH2_HUMANMD2BP_HUMANBioGRID, DIP, HPRD, IntAct11591653 16169070 16189514 19060904 26324890 29973720 31515488 32296183 details
PCH2_HUMANCK054_HUMANBioGRID, HPRD, IntAct16189514 19060904 32296183 details
PCH2_HUMANGRIN2_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANLASP1_HUMANBioGRID, HPRD, IntAct, MINT16189514 19060904 21516116 25416956 32296183 details
PCH2_HUMANCOMT_HUMANBioGRID, HPRD, IntAct16189514 19060904 25416956 details
PCH2_HUMANPP2AA_HUMANBioGRID, HPRD, IntAct16189514 19060904 32296183 details
PCH2_HUMANTEX37_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
PCH2_HUMANASB13_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
PCH2_HUMANNB5R2_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
PCH2_HUMANSTALP_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANHDHD3_HUMANBioGRID, HPRD, IntAct16189514 19060904 32296183 details
PCH2_HUMANGPSM1_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANCAR14_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANZN655_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANNDKM_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
PCH2_HUMANMEAK7_HUMANBioGRID, HPRD, IntAct16189514 19060904 31515488 details
PCH2_HUMANLNX1_HUMANBioGRID, HPRD, IntAct16189514 25416956 29892012 32296183 details
PCH2_HUMANRBPMS_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANDTX2_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANPLS4_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
PCH2_HUMANSBP1_HUMANBioGRID, HPRD, IntAct16189514 29892012 31515488 32296183 details
PCH2_HUMANPRKN_HUMANBioGRID, HPRD, IntAct16189514 19060904 24722188 details
PCH2_HUMANGLCTK_HUMANBioGRID, HPRD, IntAct16189514 19060904 25416956 32296183 details
PCH2_HUMANADA15_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANDDAH2_HUMANBioGRID, HPRD, IntAct16189514 19060904 32296183 details
PCH2_HUMANLOXL4_HUMANBioGRID, HPRD, IntAct16189514 19060904 25416956 details
PCH2_HUMANSC24A_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANSMUG1_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANSIGL5_HUMANBioGRID, HPRD, IntAct16189514 25416956 details
PCH2_HUMANPBLD_HUMANBioGRID, HPRD, IntAct16189514 25416956 details
PCH2_HUMANNIF3L_HUMANBioGRID, HPRD, IntAct16189514 19060904 details
PCH2_HUMANGALT_HUMANBioGRID, HPRD, IntAct16189514 26871637 details
PCH2_HUMANPLS3_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
PCH2_HUMANINT11_HUMANBioGRID, HPRD, IntAct16189514 28514442 details
PCH2_HUMANNTAQ1_HUMANBioGRID, HPRD, IntAct16189514 19060904 details
PCH2_HUMANKRA32_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANPLK3_HUMANBioGRID, HPRD, IntAct16189514 details
PCH2_HUMANARL11_HUMANBioGRID, HPRD, IntAct16189514 19060904 31515488 details
PCH2_HUMANMD2L2_HUMANBioGRID, IntAct19060904 30022168 details
PCH2_HUMANSTABP_HUMANBioGRID, IntAct19060904 31515488 details
PCH2_HUMANCRBA2_HUMANBioGRID, IntAct19060904 32296183 details
PCH2_HUMANPAR11_HUMANBioGRID, IntAct19060904 details
PCH2_HUMANLRC61_HUMANBioGRID, IntAct19060904 details
PCH2_HUMANMPPD2_HUMANBioGRID, IntAct19060904 21516116 25416956 32296183 details
PCH2_HUMANRHXF2_HUMANBioGRID, IntAct19060904 25416956 32296183 details
PCH2_HUMANARSA_HUMANBioGRID, IntAct, MINT21516116 25416956 25910212 26871637 32296183 details
PCH2_HUMANUBC9_HUMANBioGRID, MINT21516116 32296183 details
PCH2_HUMANSCP2_HUMANBioGRID, IntAct, MINT21516116 25416956 details
PCH2_HUMANFND3B_HUMANBioGRID, IntAct, MINT21516116 25416956 31515488 32296183 details
PCH2_HUMANMET15_HUMANBioGRID, IntAct25416956 32296183 details
PCH2_HUMANDPYL4_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANTCTP_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANSYQ_HUMANBioGRID, IntAct25416956 32296183 details
PCH2_HUMANKR121_HUMANBioGRID, IntAct25416956 32296183 details
PCH2_HUMANKR122_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANDIP2A_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANKAT1_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANSPRY7_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANKR261_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANMORN3_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANCD033_HUMANBioGRID, IntAct25416956 31515488 32296183 details
PCH2_HUMANTNR6A_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANM1AP_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANPELI1_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANLLR1_HUMANBioGRID, IntAct25416956 details
PCH2_HUMANTINAL_HUMANBioGRID, IntAct25416956 32296183 details
PCH2_HUMANSEM4G_HUMANBioGRID, HPRD, IntAct16189514 25416956 details
PCH2_HUMANNAGA_HUMANBioGRID, IntAct25416956 32296183 details
PCH2_HUMANAAPK2_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANKR124_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANPSB8_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANPRR13_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANVENTX_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANIGFN1_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANMYEOV_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANTET5B_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANC170B_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANPAX9_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANSHRPN_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANCDIN1_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANSDCB1_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANDCTN3_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANKRA61_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANKRA62_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANCS054_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANSEM3B_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANANR10_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANIL2RB_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANRPAB5_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANPCSK5_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANCLIP4_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANRNF4_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANEF2KT_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANINCA1_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANZMYM5_HUMANBioGRID, IntAct32296183 details
PCH2_HUMANFBLN5_HUMANBioGRID, IntAct25910212 details
PCH2_HUMANVDR_HUMANBioGRID, IntAct25910212 details
PCH2_HUMANCDC20_HUMANBioGRID, DIP26324890 29973720 details
PCH2_HUMANMD2L1_HUMANBioGRID, DIP25012665 26324890 26986935 29973720 details
PCH2_HUMANPLAC8_HUMANBioGRID, HPRD16189514 details
PCH2_HUMANCD99_HUMANBioGRID, HPRD15388255 details
PCH2_HUMANMVP_HUMANBioGRID24722188 details
PCH2_HUMANBUB1B_HUMANBioGRID25012665 26324890 details
PCH2_HUMANPCMD2_HUMANBioGRID25416956 details
PCH2_HUMANZNF34_HUMANBioGRID25416956 32296183 details
PCH2_HUMANMGT5B_HUMANBioGRID25416956 32296183 details
PCH2_HUMANPROP_HUMANBioGRID26871637 details
PCH2_HUMANFBX8_HUMANBioGRID26871637 details
PCH2_HUMANSRB4D_HUMANBioGRID32296183 details
PCH2_HUMANMBLC1_HUMANBioGRID32296183 details
PCH2_HUMANSUMO2_HUMANBioGRID32786267 details
PCH2_HUMANTHB_HUMANHPRD7776974 details
PCH2_HUMANTNR1B_HUMANIntAct14743216 details
PCH2_HUMANMD1L1_HUMANBioGRID25012665 details
PCH2_HUMANPSMA8_HUMANBioGRID31437213 details