Entity Details

Primary name PI5PA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15735
EntryNamePI5PA_HUMAN
FullNamePhosphatidylinositol 4,5-bisphosphate 5-phosphatase A
TaxID9606
Evidenceevidence at protein level
Length1006
SequenceStatuscomplete
DateCreated2003-04-30
DateModified2021-06-02

Ontological Relatives

GenesINPP5J

GO terms

Show/Hide Table
GOName
GO:0001726 ruffle
GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004445 inositol-polyphosphate 5-phosphatase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006661 phosphatidylinositol biosynthetic process
GO:0010977 negative regulation of neuron projection development
GO:0017124 SH3 domain binding
GO:0019898 extrinsic component of membrane
GO:0030426 growth cone
GO:0031115 negative regulation of microtubule polymerization
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0043198 dendritic shaft
GO:0043647 inositol phosphate metabolic process
GO:0046855 inositol phosphate dephosphorylation
GO:0046856 phosphatidylinositol dephosphorylation
GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000300 Inositol polyphosphate-related phosphataseDomainDomain
IPR005135 Endonuclease/exonuclease/phosphataseDomainDomain
IPR036691 Endonuclease/exonuclease/phosphatase superfamilyFamilyHomologous superfamily
IPR041611 SKICH domainDomainDomain

Diseases

Show/Hide Table