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Entity Details
Primary name
DPYL2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q16555
EntryName
DPYL2_HUMAN
FullName
Dihydropyrimidinase-related protein 2
TaxID
9606
Evidence
evidence at protein level
Length
572
SequenceStatus
complete
DateCreated
1998-07-15
DateModified
2021-06-02
Ontological Relatives
Genes
DPYSL2
GO terms
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GO
Name
GO:0004157
dihydropyrimidinase activity
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0005886
plasma membrane
GO:0006139
nucleobase-containing compound metabolic process
GO:0006897
endocytosis
GO:0007010
cytoskeleton organization
GO:0007165
signal transduction
GO:0007399
nervous system development
GO:0007411
axon guidance
GO:0007420
brain development
GO:0008017
microtubule binding
GO:0030516
regulation of axon extension
GO:0042802
identical protein binding
GO:0045664
regulation of neuron differentiation
GO:0070062
extracellular exosome
Subcellular Location
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Subcellular Location
Cytoplasm
Membrane
Domains
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Domain
Name
Category
Type
IPR006680
Amidohydrolase-related
Domain
Domain
IPR011059
Metal-dependent hydrolase, composite domain superfamily
Family
Homologous superfamily
IPR011778
Hydantoinase/dihydropyrimidinase
Family
Family
IPR030615
Dihydropyrimidinase-related protein 2
Family
Family
IPR032466
Metal-dependent hydrolase
Family
Homologous superfamily
Diseases
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Drugs
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Drug
Name
Source
Type
DB11638
Artenimol
Drugbank
small molecule
Interactions
24 interactions
Interactor
Partner
Sources
Publications
Link
DPYL2_HUMAN
DISC1_HUMAN
BioGRID, IntAct
17043677
31413325
details
DPYL2_HUMAN
DPYL2_HUMAN
BioGRID, IntAct, MINT
21516116
25416956
29892012
31515488
32296183
details
DPYL2_HUMAN
LEF1_HUMAN
BioGRID, IntAct
21988832
details
DPYL2_HUMAN
DPYL1_HUMAN
BioGRID, HPRD, IntAct, MINT
12482610
21900206
24722188
32296183
details
DPYL2_HUMAN
DPYL4_HUMAN
BioGRID, MINT
21900206
details
DPYL2_HUMAN
HD_HUMAN
IntAct
17500595
32814053
details
DPYL2_HUMAN
DPYL3_HUMAN
BioGRID, IntAct
25416956
28514442
29892012
31515488
32296183
details
DPYL2_HUMAN
DPYL5_HUMAN
BioGRID, HPRD, IntAct
10956643
25416956
28514442
29892012
31515488
32296183
details
DPYL2_HUMAN
GORS2_HUMAN
BioGRID, IntAct
25416956
29892012
31515488
32296183
details
DPYL2_HUMAN
TNIK_HUMAN
BioGRID, IntAct
17043677
31413325
details
DPYL2_HUMAN
AP2A1_HUMAN
BioGRID
12942088
details
DPYL2_HUMAN
NUMB_HUMAN
BioGRID, HPRD
11121447
12942088
details
DPYL2_HUMAN
UBC9_HUMAN
BioGRID
27940916
details
DPYL2_HUMAN
CDC42_HUMAN
BioGRID
31478661
details
DPYL2_HUMAN
MILK1_HUMAN
UniProt
20801876
details
DPYL2_HUMAN
NMDE2_HUMAN
UniProt
30871964
details
DPYL2_HUMAN
PP1A_HUMAN
BioGRID
17683050
details
DPYL2_HUMAN
PP1G_HUMAN
BioGRID
17683050
details
DPYL2_HUMAN
PRDX2_HUMAN
BioGRID
30315937
details
DPYL2_HUMAN
PREX1_HUMAN
BioGRID
26792863
details
DPYL2_HUMAN
GSK3B_HUMAN
BioGRID, HPRD
15652488
31561361
details
DPYL2_HUMAN
ROCK1_HUMAN
HPRD
10818093
12482610
details
DPYL2_HUMAN
PLD2_HUMAN
HPRD
11741937
details
DPYL2_HUMAN
TBB2A_HUMAN
HPRD
12134159
details
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