Entity Details

Primary name PDGFA
Entity type gene
Source Source Link

Details

PrimaryID5154
RefseqGeneNG_029727
SymbolPDGFA
Nameplatelet derived growth factor subunit A
Chromosome7
Location7p22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-12-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPDGFA_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000165 MAPK cascade
GO:0001525 angiogenesis
GO:0001775 cell activation
GO:0001942 hair follicle development
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002576 platelet degranulation
GO:0005161 platelet-derived growth factor receptor binding
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005796 Golgi lumen
GO:0005902 microvillus
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0009611 response to wounding
GO:0009887 animal organ morphogenesis
GO:0009986 cell surface
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process
GO:0010544 negative regulation of platelet activation
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014910 regulation of smooth muscle cell migration
GO:0030031 cell projection assembly
GO:0030036 actin cytoskeleton organization
GO:0030198 extracellular matrix organization
GO:0030335 positive regulation of cell migration
GO:0031093 platelet alpha granule lumen
GO:0031954 positive regulation of protein autophosphorylation
GO:0032956 regulation of actin cytoskeleton organization
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
GO:0042060 wound healing
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043588 skin development
GO:0046982 protein heterodimerization activity
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048146 positive regulation of fibroblast proliferation
GO:0048286 lung alveolus development
GO:0048407 platelet-derived growth factor binding
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0050919 negative chemotaxis
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070851 growth factor receptor binding
GO:1990401 embryonic lung development

Diseases

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